<p>Numerous studies have shown that viruses are present in a variety of environments on Earth, acting as drivers of biogeochemical cycles and powerful selective forces. Among them, giant viruses of amoebae have garnered attention from the scientific community due to their large particles and extensive genomes. Here, we describe the discovery of one of the largest tailed viruses in the known virosphere (averaging 1350 nm), named Naiavirus. This virus, isolated from a swamp biome in Brazil, has particles with a never-before-seen morphology and composition, and represents the first giant amoeba virus with an external envelope covering the capsid and extending over a flexible tail region. The Naiavirus genome, with nearly 1 million base pairs, reveals a unique set of genes, and does not resemble any other virus previously isolated so far.</p>

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Naiavirus: an enveloped giant virus with a pleomorphic, flexible tail

  • Matheus Rodrigues,
  • Victória Queiroz,
  • Thalita Arantes,
  • Henrique Limborço,
  • Bruna Neiva,
  • Nidia Arias,
  • Talita Machado,
  • Matheus Barcelos,
  • Juliana R. Cortines,
  • Otavio Henrique Thiemann,
  • Rafael Elias Marques,
  • Talita Diniz Melo-Hanchuk,
  • Eliana Leonor Hurtado Celis,
  • João Pessoa Araujo Jr,
  • Erik Reis,
  • Luiz Carlos Junior Alcantara,
  • Cezar Batista Cunha Santos,
  • Abdeali Jivaji,
  • Rodrigo A. L. Rodrigues,
  • Frank O. Aylward,
  • Jônatas Santos Abrahão

摘要

Numerous studies have shown that viruses are present in a variety of environments on Earth, acting as drivers of biogeochemical cycles and powerful selective forces. Among them, giant viruses of amoebae have garnered attention from the scientific community due to their large particles and extensive genomes. Here, we describe the discovery of one of the largest tailed viruses in the known virosphere (averaging 1350 nm), named Naiavirus. This virus, isolated from a swamp biome in Brazil, has particles with a never-before-seen morphology and composition, and represents the first giant amoeba virus with an external envelope covering the capsid and extending over a flexible tail region. The Naiavirus genome, with nearly 1 million base pairs, reveals a unique set of genes, and does not resemble any other virus previously isolated so far.