Scholarlink

<p>Early blood pressure (BP) reduction following bariatric surgery can be observed early, yet the mechanisms remain incompletely understood. Our study evaluated short-term changes in BP and cardiac hemodynamics following sleeve gastrectomy. Bedside BP, 24-h ambulatory blood pressure monitoring (ABPM), and echocardiography were performed one-week [1 W] and one-month [1 M] post-surgery in 40 patients (pts) (mean age 44.8 years, body mass index (BMI) 42.2 kg/m<sup>2</sup>, 58% females). We found that the mean decrease in bedside SBP was 5.2 mmHg (<i>p</i> &lt; 0.05)[1 W] and 10.4 mmHg (<i>p</i> &lt; 0.05) [1 M] and in ABPM SBP 6.5 mmHg (<i>p</i> &lt; 0.05)[1 W] and 10.5 mmHg (<i>p</i> &lt; 0.05)[1 M]. Mean change in bedside and ABPM heart rate (HR)[1 W] was (-3.2) and an increase of 0.2 bpm (ns) and (-8.4 bpm) and (-6.5 bpm) (<i>p</i> &lt; 0.05)[1 M], respectively. Mean stroke volume (SV) and cardiac output (CO) change at [1 W] was (-6.6 ml) and (-0.88 l/min) (both p &lt; 0.05) and [1 M] ( + 1.4 ml) (ns), and (-0.94 l/min) (<i>p</i> &lt; 0.05). Mitral valve velocity time integral (MV VTI) and early diastolic mitral inflow (E) velocity significantly decreased at [1 W] and returned to baseline at [1 M] (MV VTI 20.62 ± 4.0, 18.8 ± 3.3, <i>p</i> &lt; 0.05 and 21.5 ± 3.7 cm ns, E 77.7 ± 16.8, 65.9 ± 14.2, <i>p</i> &lt; 0.05, and 75.4 ± 11.6 cm/s, ns). Our results indicate that early postoperative BP reduction is accompanied by a transient decrease in CO, associated with reduced SV and echocardiographic changes suggestive of decreased preload. However, individual changes in CO did not independently predict the magnitude of BP reduction, indicating that the precise mechanisms underlying early postoperative BP reduction remain to be established and are multifactorial.</p><p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

The early impact of bariatric surgery on blood pressure: A hemodynamic analysis using echocardiography in a prospective observational cohort study

  • 期刊论文

  • 发表日期：

    2026年3月25日

查看全文
  • Grzegorz Styczynski,
  • Piotr Kalinowski,
  • Katarzyna Cienszkowska,
  • Marta Ludwiczak,
  • Jakub Strzelczyk,
  • Cezary Szmigielski

摘要

Early blood pressure (BP) reduction following bariatric surgery can be observed early, yet the mechanisms remain incompletely understood. Our study evaluated short-term changes in BP and cardiac hemodynamics following sleeve gastrectomy. Bedside BP, 24-h ambulatory blood pressure monitoring (ABPM), and echocardiography were performed one-week [1 W] and one-month [1 M] post-surgery in 40 patients (pts) (mean age 44.8 years, body mass index (BMI) 42.2 kg/m2, 58% females). We found that the mean decrease in bedside SBP was 5.2 mmHg (p < 0.05)[1 W] and 10.4 mmHg (p < 0.05) [1 M] and in ABPM SBP 6.5 mmHg (p < 0.05)[1 W] and 10.5 mmHg (p < 0.05)[1 M]. Mean change in bedside and ABPM heart rate (HR)[1 W] was (-3.2) and an increase of 0.2 bpm (ns) and (-8.4 bpm) and (-6.5 bpm) (p < 0.05)[1 M], respectively. Mean stroke volume (SV) and cardiac output (CO) change at [1 W] was (-6.6 ml) and (-0.88 l/min) (both p < 0.05) and [1 M] ( + 1.4 ml) (ns), and (-0.94 l/min) (p < 0.05). Mitral valve velocity time integral (MV VTI) and early diastolic mitral inflow (E) velocity significantly decreased at [1 W] and returned to baseline at [1 M] (MV VTI 20.62 ± 4.0, 18.8 ± 3.3, p < 0.05 and 21.5 ± 3.7 cm ns, E 77.7 ± 16.8, 65.9 ± 14.2, p < 0.05, and 75.4 ± 11.6 cm/s, ns). Our results indicate that early postoperative BP reduction is accompanied by a transient decrease in CO, associated with reduced SV and echocardiographic changes suggestive of decreased preload. However, individual changes in CO did not independently predict the magnitude of BP reduction, indicating that the precise mechanisms underlying early postoperative BP reduction remain to be established and are multifactorial.