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Background <p>Intraocular foreign bodies (IOFBs) constitute a significant public health concern that hinders the accumulation of human capital in countries in Asia. This research aims to identify and project the time trend of the IOFB disease burden in Asia to 2035.</p> Methods <p>We utilised data collected from the Global Health Data Exchange (GHDx) query tool. Time Trends of disability-adjusted life years (DALYs) and incidence of IOFBs were calculated. Age- and gender-specific disease burden of IOFBs in 2019 was also analysed. A Bayesian age-period cohort (BAPC) model with integrated nested Laplace approximations (INLA) was applied to project the number and rate of the disease burden attributable to IOFB from 2020 to 2035.</p> Results <p>In Asia, the DALYs number increased from 290,521.62 (95% UI: 146,816.5–513,604.1) in 1990 to 388,363.39 (95% UI: 206,296.3–668,164.9) in 2019. The number of DALYs showed an upward trend until the age of 45–49 years, and then decreased in later age groups. The age-standardised incidence rate (ASIR) of China is projected to increase substantially from 719.03 in 2019 to 3127.06 in 2035. Singapore is projected to experience a slight decline, while the remaining six countries are projected to have slight, steady increases in ASIR.</p> Conclusion <p>Countries in Asia are facing a huge disease burden of IOFB, and ASIRs are projected to increase over the next 15 years in most Asian countries. These findings contribute valuable evidence-based guidance for public health policy in disease prevention, medical planning and resource allocation pertaining to IOFBs in Asia.</p>

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Intraocular foreign bodies in Asia: insights from the Global Burden of Disease 2019 Study

  • 期刊论文

  • 发表日期：

    2026年3月14日

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  • Bo Yang,
  • Haozhe Yu,
  • Richard Blanch,
  • Annette Hoskin,
  • Amanda M. Staudt,
  • Rupesh Agrawal,
  • Yun Feng

摘要

Background

Intraocular foreign bodies (IOFBs) constitute a significant public health concern that hinders the accumulation of human capital in countries in Asia. This research aims to identify and project the time trend of the IOFB disease burden in Asia to 2035.

Methods

We utilised data collected from the Global Health Data Exchange (GHDx) query tool. Time Trends of disability-adjusted life years (DALYs) and incidence of IOFBs were calculated. Age- and gender-specific disease burden of IOFBs in 2019 was also analysed. A Bayesian age-period cohort (BAPC) model with integrated nested Laplace approximations (INLA) was applied to project the number and rate of the disease burden attributable to IOFB from 2020 to 2035.

Results

In Asia, the DALYs number increased from 290,521.62 (95% UI: 146,816.5–513,604.1) in 1990 to 388,363.39 (95% UI: 206,296.3–668,164.9) in 2019. The number of DALYs showed an upward trend until the age of 45–49 years, and then decreased in later age groups. The age-standardised incidence rate (ASIR) of China is projected to increase substantially from 719.03 in 2019 to 3127.06 in 2035. Singapore is projected to experience a slight decline, while the remaining six countries are projected to have slight, steady increases in ASIR.

Conclusion

Countries in Asia are facing a huge disease burden of IOFB, and ASIRs are projected to increase over the next 15 years in most Asian countries. These findings contribute valuable evidence-based guidance for public health policy in disease prevention, medical planning and resource allocation pertaining to IOFBs in Asia.