Scholarlink

Background/Objectives <p>Maintaining an adequate vitamin D status is challenging for part of the Dutch adults; therefore, use of vitamin D supplements is advised for certain subgroups. Recent studies on vitamin D status in the general Dutch population are lacking. This study aimed to investigate vitamin D status in a Dutch adult population and how it compared to twelve years earlier.</p> Subjects/Methods <p>Blood samples from participants of the Lifelines cohort collected in March 2023 were analysed for 25(OH)D₃ concentration (<i>N</i> = 1000). Log 25(OH)D₃ concentrations and proportion participants with a 25(OH)D₃ concentration &lt;30 (18–69 yrs)/&lt;50 nmol/L (≥70 yrs) were compared across gender and age groups (18–49, 50–69, and ≥70 yrs) using t-tests and ANOVA. Vitamin D status in March 2023 was compared to the status in March 2011 (<i>N</i> = 1221). Additionally, monthly variation in vitamin D status within 2011 was studied.</p> Results <p>Men had a significantly lower median 25(OH)D₃ concentration compared to women. 25(OH)D₃ concentration increased with age. Vitamin D deficiency was observed in 7% of women 50–69 yrs and in 26% of men and 13% of women ≥70 yrs. Compared to March 2011, 25(OH)D₃ concentration in March 2023 was significantly higher (median 45–49 vs. 54–75 nmol/L). Vitamin D status throughout 2011 showed highest deficiency levels in winter.</p> Conclusions <p>Vitamin D status improved between 2011 and 2023, but still up to a quarter of men and women in different age groups were vitamin D deficient at the end of the winter of 2023. Vitamin D status was highest in the subgroups with supplementation advice.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Vitamin D status of adults in the North of the Netherlands: cross-sectional results from the Lifelines cohort study

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年9月25日

查看全文
  • Marieke R. Verbakel,
  • Janneke Verkaik-Kloosterman,
  • Ceciel S. Dinnissen,
  • Nynke Koopman,
  • Marga C. Ocké,
  • Marjolein H. de Jong

摘要

Background/Objectives

Maintaining an adequate vitamin D status is challenging for part of the Dutch adults; therefore, use of vitamin D supplements is advised for certain subgroups. Recent studies on vitamin D status in the general Dutch population are lacking. This study aimed to investigate vitamin D status in a Dutch adult population and how it compared to twelve years earlier.

Subjects/Methods

Blood samples from participants of the Lifelines cohort collected in March 2023 were analysed for 25(OH)D₃ concentration (N = 1000). Log 25(OH)D₃ concentrations and proportion participants with a 25(OH)D₃ concentration <30 (18–69 yrs)/<50 nmol/L (≥70 yrs) were compared across gender and age groups (18–49, 50–69, and ≥70 yrs) using t-tests and ANOVA. Vitamin D status in March 2023 was compared to the status in March 2011 (N = 1221). Additionally, monthly variation in vitamin D status within 2011 was studied.

Results

Men had a significantly lower median 25(OH)D₃ concentration compared to women. 25(OH)D₃ concentration increased with age. Vitamin D deficiency was observed in 7% of women 50–69 yrs and in 26% of men and 13% of women ≥70 yrs. Compared to March 2011, 25(OH)D₃ concentration in March 2023 was significantly higher (median 45–49 vs. 54–75 nmol/L). Vitamin D status throughout 2011 showed highest deficiency levels in winter.

Conclusions

Vitamin D status improved between 2011 and 2023, but still up to a quarter of men and women in different age groups were vitamin D deficient at the end of the winter of 2023. Vitamin D status was highest in the subgroups with supplementation advice.