Scholarlink

Objective <p>To compare acute effects of continuous moderate-intensity exercise (CME) and low-volume high-intensity interval exercise (LV-HIIE) on appetite responses between South Asians and white Europeans with non-diabetic hyperglycaemia.</p> Methods <p>Thirteen white Europeans and 10 South Asians (age 50–74 years) completed three, 5-h experimental conditions (CME, LV-HIIE, control) in randomised sequences. Standardised meals were provided at 0 and 3 h. Exercise involved a 25-min LV-HIIE or 35-min CME bout that ended at 2 h. Subjective appetite perceptions and appetite-related hormones (glucagon-like peptide-1 (GLP-1), peptide YY (PYY), acylated ghrelin (AG)) were measured at 0, 0.5, 1, 2, 3, 3.5, 4 and 5 h. Time-averaged total area under the curve (TAUC; 1–5 h) was analysed, adjusted for age, sex, and pre-intervention time-averaged TAUC (0–1 h).</p> Results <p>Total GLP-1 was higher in LV-HIIE (mean difference [95% CI] 4.3 [1.5, 7.1] pmol/L h) and CME (4.5 [1.4, 7.7] pmol/L h) versus control (condition effect <i>P</i> = 0.01), but exercise had no effect on the other outcomes in the whole study population (<i>P</i> ≥ 0.28). Appetite responses to exercise were similar between ethnicities for total GLP-1 and total PYY (interaction <i>P</i> ≥ 0.11), but subtle differences emerged for AG and overall appetite (interaction <i>P</i> ≤ 0.02). AG was higher and overall appetite lower in LV-HIIE versus CME in South Asians whilst overall appetite was higher in LV-HIIE versus CME in white Europeans, but neither exercise bout was different to control.</p> Discussion <p>Single LV-HIIE and CME bouts increased total GLP-1 in individuals with non-diabetic hyperglycaemia, but exercise-related appetite responses were not strongly modulated by exercise intensity or ethnicity.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

The acute effects of moderate-intensity continuous or high-intensity interval exercise on appetite and appetite-related hormones in South Asian and white European adults with non-diabetic hyperglycaemia

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年5月27日

查看全文
  • Tonghui Shen,
  • Alice E. Thackray,
  • Jack A. Sargeant,
  • Thomas Yates,
  • James A. King,
  • Scott A. Willis,
  • David J. Stensel

摘要

Objective

To compare acute effects of continuous moderate-intensity exercise (CME) and low-volume high-intensity interval exercise (LV-HIIE) on appetite responses between South Asians and white Europeans with non-diabetic hyperglycaemia.

Methods

Thirteen white Europeans and 10 South Asians (age 50–74 years) completed three, 5-h experimental conditions (CME, LV-HIIE, control) in randomised sequences. Standardised meals were provided at 0 and 3 h. Exercise involved a 25-min LV-HIIE or 35-min CME bout that ended at 2 h. Subjective appetite perceptions and appetite-related hormones (glucagon-like peptide-1 (GLP-1), peptide YY (PYY), acylated ghrelin (AG)) were measured at 0, 0.5, 1, 2, 3, 3.5, 4 and 5 h. Time-averaged total area under the curve (TAUC; 1–5 h) was analysed, adjusted for age, sex, and pre-intervention time-averaged TAUC (0–1 h).

Results

Total GLP-1 was higher in LV-HIIE (mean difference [95% CI] 4.3 [1.5, 7.1] pmol/L h) and CME (4.5 [1.4, 7.7] pmol/L h) versus control (condition effect P = 0.01), but exercise had no effect on the other outcomes in the whole study population (P ≥ 0.28). Appetite responses to exercise were similar between ethnicities for total GLP-1 and total PYY (interaction P ≥ 0.11), but subtle differences emerged for AG and overall appetite (interaction P ≤ 0.02). AG was higher and overall appetite lower in LV-HIIE versus CME in South Asians whilst overall appetite was higher in LV-HIIE versus CME in white Europeans, but neither exercise bout was different to control.

Discussion

Single LV-HIIE and CME bouts increased total GLP-1 in individuals with non-diabetic hyperglycaemia, but exercise-related appetite responses were not strongly modulated by exercise intensity or ethnicity.