Cardiovascular risks in men with prostate cancer: a pragmatic, clinician-oriented review of risk stratification and management strategies
摘要
Recent advances in prostate cancer management have improved overall survival and quality of life for those afflicted. However, these patients continue to suffer from a high burden of cardiovascular disease through a variety of mechanisms, including both the cancer itself as well as prostate cancer-specific treatments.
Subjects/MethodsCardiovascular disease is now the leading cause of death in this population, and current data suggests that many patients remain sub-optimally controlled from a risk factor standpoint. There is a lack of consensus and standardized guidelines on cardiovascular risk stratification and specific management strategies in the urology, medical oncology, radiation oncology, and primary care settings.
Results/ConclusionsWe review available literature and provide a cardiovascular risk stratification schema for prostate cancer patients that clinicians in each of these settings can utilize. We also highlight a shared decision-making model, consistent risk restratification, and social determinants of health as care priorities to optimize cardiovascular health for this at-risk population.