Flexible bioelectronic sensors promote the advancement of wearable ultrasound technology in the medicine
摘要
Continuous and real-time monitoring of the subtle spatio-temporal changes in human physiological states are essential for daily diagnosis and treatment. Additionally, the capacity for monitoring is frequently restricted by available materials and specific application contexts. Wearable Flexible Ultrasound Biosensors (WFUBs) can be comfortably applied to the human body and have the functions of continuous monitoring and interventional therapy. The review summarized recent advances in the way WFUBs acquire vital data from particular biological tissue, the structural design and material selection, including the substrate, electrical connection, electrode, and the material synthesis of biosensors. In addition, the aspects of performance improvement of WFUBs were summarized, and the applications of wearable ultrasound systems in health care, diagnostic imaging, and interventional therapy were further discussed. Finally, the challenges and future research directions in the field of next generation WFUBs were explored.