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<p>Hydronephrosis, a serious complication of ureteral stents, can lead to deterioration of renal function due to prolonged increased intrarenal pressure. Currently, the only way to diagnose hydronephrosis is radiographic imaging, and a continuous, non-invasive method is not available. This study introduces the ureteral stent sleeve, UroSleeve, a modular wireless pressure monitoring system that is designed to integrate seamlessly with standard ureteral stents without altering their existing designs or manufacturing processes. The UroSleeve incorporates a flexible printed-circuit-board-based spiral antenna and a surface-micromachined capacitive pressure sensor, forming an inductor-capacitor tank circuit capable of wireless telemetry through near-field inductive coupling. The device was evaluated in an ex vivo porcine kidney model whose internal pressure was externally controlled to mimic a hydronephrosis condition, and kidney pressure changes were successfully monitored by detecting shifts in the resonant frequency of the device. Key results demonstrated a high sensitivity with -5.3 ± 0.74 kHz/mmHg with a baseline resonant frequency of 15.234 MHz at 8.5 mmHg. The frequency response showed a strong correlation with kidney pressure, and the device maintained consistent performance in a relevant biological environment. The results indicate that UroSleeve offers a practical and versatile solution for wireless intrarenal pressure monitoring, amenable to future clinical translation.</p><p></p>

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Ureteral stent sleeve for early detection of hydronephrosis

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月18日

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  • Nabil Shalabi,
  • Kyle Searles,
  • Roman Herout,
  • Khaled Almutairi,
  • Ben H. Chew,
  • Dirk Lange,
  • Kenichi Takahata

摘要

Hydronephrosis, a serious complication of ureteral stents, can lead to deterioration of renal function due to prolonged increased intrarenal pressure. Currently, the only way to diagnose hydronephrosis is radiographic imaging, and a continuous, non-invasive method is not available. This study introduces the ureteral stent sleeve, UroSleeve, a modular wireless pressure monitoring system that is designed to integrate seamlessly with standard ureteral stents without altering their existing designs or manufacturing processes. The UroSleeve incorporates a flexible printed-circuit-board-based spiral antenna and a surface-micromachined capacitive pressure sensor, forming an inductor-capacitor tank circuit capable of wireless telemetry through near-field inductive coupling. The device was evaluated in an ex vivo porcine kidney model whose internal pressure was externally controlled to mimic a hydronephrosis condition, and kidney pressure changes were successfully monitored by detecting shifts in the resonant frequency of the device. Key results demonstrated a high sensitivity with -5.3 ± 0.74 kHz/mmHg with a baseline resonant frequency of 15.234 MHz at 8.5 mmHg. The frequency response showed a strong correlation with kidney pressure, and the device maintained consistent performance in a relevant biological environment. The results indicate that UroSleeve offers a practical and versatile solution for wireless intrarenal pressure monitoring, amenable to future clinical translation.