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<p>By combining mid-infrared excitation with polarization-resolved photoacoustics, Park et al. introduce a novel label-free approach to visualize both molecular composition and fiber alignment in engineered tissues. This dual-contrast framework, termed MIR-DS-PAM, offers a new path toward analytical, quantitative histopathology.</p>

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Revealing hidden tissue architecture with mid-infrared dichroism photoacoustic microscopy

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月24日

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  • Colton McGarraugh,
  • Soon-Woo Cho,
  • Junjie Yao

摘要

By combining mid-infrared excitation with polarization-resolved photoacoustics, Park et al. introduce a novel label-free approach to visualize both molecular composition and fiber alignment in engineered tissues. This dual-contrast framework, termed MIR-DS-PAM, offers a new path toward analytical, quantitative histopathology.