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Objective <p>Skin-to-skin care (SSC) of extremely preterm infants are often withheld early in life due to the risk of hypothermia. We aimed to evaluate if SSC is non-inferior to incubator care with regard to maintaining normothermia.</p> Study design <p>A non-inferiority study was conducted in infants with a gestational age of 22–25 weeks, during October 2023-January 2026. Axillary temperatures were obtained at three time points; in the incubator, during SSC, and immediately after transfer back to the incubator.</p> Results <p>Body temperature data were obtained from SSC sessions (<i>n</i> = 125) in the first 2 weeks in 46 eligible infants, among whom 20 were born at 22–23 weeks. In terms of the risk for hypothermia ( &lt; 36.5 °C), SSC was non-inferior to incubator care, and the risk of hypothermia decreased by 5 percentage points (<i>p</i> &lt; 0.001).</p> Conclusion <p>Infants born at 22–25 weeks can maintain thermoneutrality during SSC if carried out according to a delineated protocol.</p>

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Thermal stability during early skin-to-skin vs incubator care in infants born at 22–25 weeks’ gestation: a non-inferiority prospective cohort study

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  • 发表日期：

    2026年7月21日

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  • Veronica Starke,
  • Ylva Thernström Blomqvist,
  • Lars Lindhagen,
  • Johan Ågren,
  • Victoria Karlsson

摘要

Objective

Skin-to-skin care (SSC) of extremely preterm infants are often withheld early in life due to the risk of hypothermia. We aimed to evaluate if SSC is non-inferior to incubator care with regard to maintaining normothermia.

Study design

A non-inferiority study was conducted in infants with a gestational age of 22–25 weeks, during October 2023-January 2026. Axillary temperatures were obtained at three time points; in the incubator, during SSC, and immediately after transfer back to the incubator.

Results

Body temperature data were obtained from SSC sessions (n = 125) in the first 2 weeks in 46 eligible infants, among whom 20 were born at 22–23 weeks. In terms of the risk for hypothermia ( < 36.5 °C), SSC was non-inferior to incubator care, and the risk of hypothermia decreased by 5 percentage points (p < 0.001).

Conclusion

Infants born at 22–25 weeks can maintain thermoneutrality during SSC if carried out according to a delineated protocol.