Introduction <p>The objective of this study is to assess outcomes of pregnancies complicated by trisomy 13(T13) or trisomy 18(T18) and infants with T13 and T18, who were managed in a center with a perinatal palliative care program.</p> Methods <p>This is a single center retrospective cohort study of neonates with T13 or T18 and pregnancies complicated by T13 or T18 in which families opted to continue the pregnancy, that were followed at Columbia University Irving Medical Center(CUIMC) between 2008 and 2024.</p> Results <p>There were 109 pregnancies that resulted in 68 liveborn infants. Of those who met with the Neonatal Comfort Care Program(NCCP) prior to delivery, 69.9% opted for comfort care. There was no trend toward more intervention over a span of 17 years.</p> Conclusion <p>Differing from other institutions, the lack of trend toward more intervention in patients with T13 and T18 at CUIMC, may be due to the consistency of consultation practice by the NCCP.</p>

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Outcomes of patients with trisomy 13 and 18 in a center with a dedicated perinatal palliative care program

  • Sinead Brady,
  • Bryn McNamee-Tweed,
  • Yuan S. Zhang,
  • Nikolas Blenitsky,
  • Elvira Parravicini

摘要

Introduction

The objective of this study is to assess outcomes of pregnancies complicated by trisomy 13(T13) or trisomy 18(T18) and infants with T13 and T18, who were managed in a center with a perinatal palliative care program.

Methods

This is a single center retrospective cohort study of neonates with T13 or T18 and pregnancies complicated by T13 or T18 in which families opted to continue the pregnancy, that were followed at Columbia University Irving Medical Center(CUIMC) between 2008 and 2024.

Results

There were 109 pregnancies that resulted in 68 liveborn infants. Of those who met with the Neonatal Comfort Care Program(NCCP) prior to delivery, 69.9% opted for comfort care. There was no trend toward more intervention over a span of 17 years.

Conclusion

Differing from other institutions, the lack of trend toward more intervention in patients with T13 and T18 at CUIMC, may be due to the consistency of consultation practice by the NCCP.