Scholarlink

Objective <p>Evaluate whether minimally invasive surfactant therapy (MIST) reduces respiratory support duration in infants born at 28–37 weeks’ gestation with respiratory distress syndrome (RDS).</p> Study design <p>Retrospective cohort study of infants with RDS born between 28- 36 6/7 weeks’ gestation at a single center level III NICU between 2016-2024. MIST was implemented in 2020. Primary outcome was total days of respiratory support. Secondary outcomes included intubation rates, length of stay, corrected gestational age (cGA) at discharge, and incidence of bronchopulmonary dysplasia (BPD).</p> Results <p>Of 218 infants with RDS, the post MIST group had fewer days of respiratory support (8.8 vs 11 days), significantly lower rate of intubation (39% vs 100%), and shorter NICU stay (35.5 vs 41.2 days). BPD among infants &lt;32 weeks’ gestation decreased from 43% to 29%.</p> Conclusion <p>MIST was associated with reduced respiratory support and hospitalization duration in this population.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Minimally invasive surfactant therapy outcomes in infants born at 28–37 weeks’ gestation

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年6月1日

查看全文
  • Natasha Ahn,
  • Ilene Wolf,
  • Matthew Derrick

摘要

Objective

Evaluate whether minimally invasive surfactant therapy (MIST) reduces respiratory support duration in infants born at 28–37 weeks’ gestation with respiratory distress syndrome (RDS).

Study design

Retrospective cohort study of infants with RDS born between 28- 36 6/7 weeks’ gestation at a single center level III NICU between 2016-2024. MIST was implemented in 2020. Primary outcome was total days of respiratory support. Secondary outcomes included intubation rates, length of stay, corrected gestational age (cGA) at discharge, and incidence of bronchopulmonary dysplasia (BPD).

Results

Of 218 infants with RDS, the post MIST group had fewer days of respiratory support (8.8 vs 11 days), significantly lower rate of intubation (39% vs 100%), and shorter NICU stay (35.5 vs 41.2 days). BPD among infants <32 weeks’ gestation decreased from 43% to 29%.

Conclusion

MIST was associated with reduced respiratory support and hospitalization duration in this population.