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Background <p>Neonatal hypoglycemia is a common reason for neonatal intensive care unit (NICU) admission. Management variations may prolong intravenous (IV) dextrose use and NICU length of stay (LOS).</p> Methods <p>We aimed to reduce IV dextrose duration for hypoglycemic neonates transferred to the NICU by 30%. Standardization efforts included multidisciplinary team formation, guideline development, Epic SmartPhrase creation, and education. Our primary outcome measure was IV dextrose infusion duration. Secondary outcomes were LOS, percentage of patients started on IV dextrose, and number of blood draws. The process measure was guideline utilization. Balancing measures were readmissions, second IV courses, and dextrose boluses.</p> Results <p>Mean IV dextrose administration decreased from 25 to 16 h and LOS from 59 to 27 h. The number of blood draws and boluses decreased without changes in readmissions or second IV dextrose courses.</p> Conclusions <p>Our quality initiative safely reduced IV dextrose duration and NICU LOS, without significant rebound hypoglycemia.</p>

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Sweeter recovery, less intravenous fluids: a NICU quality improvement initiative for managing neonatal hypoglycemia

  • 期刊论文

  • 发表日期：

    2026年4月22日

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  • Rachel Reed,
  • Andrea Weintraub,
  • Richelle Reinhart

摘要

Background

Neonatal hypoglycemia is a common reason for neonatal intensive care unit (NICU) admission. Management variations may prolong intravenous (IV) dextrose use and NICU length of stay (LOS).

Methods

We aimed to reduce IV dextrose duration for hypoglycemic neonates transferred to the NICU by 30%. Standardization efforts included multidisciplinary team formation, guideline development, Epic SmartPhrase creation, and education. Our primary outcome measure was IV dextrose infusion duration. Secondary outcomes were LOS, percentage of patients started on IV dextrose, and number of blood draws. The process measure was guideline utilization. Balancing measures were readmissions, second IV courses, and dextrose boluses.

Results

Mean IV dextrose administration decreased from 25 to 16 h and LOS from 59 to 27 h. The number of blood draws and boluses decreased without changes in readmissions or second IV dextrose courses.

Conclusions

Our quality initiative safely reduced IV dextrose duration and NICU LOS, without significant rebound hypoglycemia.