Objective <p>Among infants born very preterm (≤32 weeks’ gestation), we compared weight-for-age ≤10th percentile (10%ile) at 36 weeks to malnutrition guidelines using z-score changes and evaluated predictors of malnutrition.</p> Study Design <p>Infants (extremely low birthweight (ELBW) <i>n</i> = 699; very low birthweight (VLBW) <i>n</i> = 878) were classified using (1) ≤10%ile and (2) malnutrition categories with z-score changes. Multiple logistic regression identified predictors of malnutrition.</p> Results <p>13% of ELBW (<i>n</i> = 91) and 15% of VLBW (<i>n</i> = 131) infants were classified as moderately/severely malnourished by losses of z-scores while weighing &gt;10%ile. Infants with chronic lung disease and/or who had any ventilator use had an increased risk of moderate/severe malnutrition with z-scores. Notably, a loss of ≤0.8 z-scores was not associated with any postnatal clinical risk factors.</p> Conclusion <p>The use of ≤10%ile for weight-for-age as a cut-off to identify growth concerns at 36 weeks postmenstrual age misclassified many preterm infants compared to malnutrition categories using z-scores.</p>

错误:搜索内容不能为空,请输入英文关键词
错误:关键词超出字数限制,请精简
高级检索

Defining growth faltering and malnutrition among very preterm infants in a neonatal intensive care unit

  • Rachel R. Rickman,
  • Anthony Rudine,
  • Steven A. Abrams,
  • Saralyn F. Foster,
  • Marcela R. Abrego,
  • Elizabeth M. Widen

摘要

Objective

Among infants born very preterm (≤32 weeks’ gestation), we compared weight-for-age ≤10th percentile (10%ile) at 36 weeks to malnutrition guidelines using z-score changes and evaluated predictors of malnutrition.

Study Design

Infants (extremely low birthweight (ELBW) n = 699; very low birthweight (VLBW) n = 878) were classified using (1) ≤10%ile and (2) malnutrition categories with z-score changes. Multiple logistic regression identified predictors of malnutrition.

Results

13% of ELBW (n = 91) and 15% of VLBW (n = 131) infants were classified as moderately/severely malnourished by losses of z-scores while weighing >10%ile. Infants with chronic lung disease and/or who had any ventilator use had an increased risk of moderate/severe malnutrition with z-scores. Notably, a loss of ≤0.8 z-scores was not associated with any postnatal clinical risk factors.

Conclusion

The use of ≤10%ile for weight-for-age as a cut-off to identify growth concerns at 36 weeks postmenstrual age misclassified many preterm infants compared to malnutrition categories using z-scores.