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Objective <p>To quantify the trajectory of lung ultrasound scores (LUSSc) and estimate their association on inpatient respiratory trajectories in preterm infants with potentially evolving bronchopulmonary dysplasia (BPD)</p> Study design <p>We measured LUSSc prospectively in infants &lt;32 weeks’ gestation weekly from 2 weeks of life through 44 weeks’ post-menstrual age (PMA) or discharge. The primary outcome was the age, in PMA, to achieve liberation of respiratory support (LRS) defined as room air or &lt; 1 L/min (F<sub>i</sub>O<sub>2</sub> = 100%).</p> Result <p>In 16 infants, 10 patients had Grade 2–3 BPD, and LUSSc declined over time. The median age to achieve LRS was 42 weeks’ PMA (33.6, 47.9). Using the maximum LUSSc each infant had between 30 and 32 weeks’ PMA, each 1-point increase in the LUSSc was independently associated with a 9-day increase in the age to achieve LRS.</p> Conclusion <p>LUSSc may serve as a diagnostic marker for inpatient respiratory trajectories of preterm infants with evolving BPD.</p>

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Trajectory of lung ultrasound scores in preterm infants at risk for bronchopulmonary dysplasia

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月13日

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  • Rachel M. Weinstein,
  • Cassandra R. Montoya,
  • Russell Horowitz,
  • Karna Murthy,
  • Leslie A. Caldarelli,
  • Stephanie M. Marshall

摘要

Objective

To quantify the trajectory of lung ultrasound scores (LUSSc) and estimate their association on inpatient respiratory trajectories in preterm infants with potentially evolving bronchopulmonary dysplasia (BPD)

Study design

We measured LUSSc prospectively in infants <32 weeks’ gestation weekly from 2 weeks of life through 44 weeks’ post-menstrual age (PMA) or discharge. The primary outcome was the age, in PMA, to achieve liberation of respiratory support (LRS) defined as room air or < 1 L/min (FiO2 = 100%).

Result

In 16 infants, 10 patients had Grade 2–3 BPD, and LUSSc declined over time. The median age to achieve LRS was 42 weeks’ PMA (33.6, 47.9). Using the maximum LUSSc each infant had between 30 and 32 weeks’ PMA, each 1-point increase in the LUSSc was independently associated with a 9-day increase in the age to achieve LRS.

Conclusion

LUSSc may serve as a diagnostic marker for inpatient respiratory trajectories of preterm infants with evolving BPD.