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Objective <p>To evaluate how the risk of unexpected newborn complications among term births varied by time of birth for 12.4 million full-term singleton births in the United States.</p> Study design <p>A population-based nationwide study. Exposures included time of birth, divided into four shifts and 42 distributed 4-h intervals. Logistic regression estimated the variations in the risk of unexpected newborn complications.</p> Result <p>The risk of unexpected newborn complications was higher during night shifts (OR 1.13, 95% CI: 1.12–1.14) and on weekends than on day shifts and weekdays. The risk of seizures and a 5-min Apgar score ≤3 increased steadily at the start of day shifts (07:00), while the risks of transfer, assisted ventilation ≥6 h, and neonatal death remained stable during day shifts. All outcomes increased during night shifts, peaking between 23:00 and 06:59.</p> Conclusion <p>Unexpected newborn complications were more frequent during night shifts and weekends, particularly between 23:00 and 06:59.</p>

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Risk of unexpected newborn complications by day of the week and time of birth in US term singleton births

  • 期刊论文

  • 发表日期：

    2025年12月22日

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  • Ruiyi Liu,
  • Chunrong Li,
  • Tian Liang,
  • Jie Yin,
  • Qiang Zeng,
  • Shi Zhao,
  • Wangnan Cao,
  • Shengzhi Sun

摘要

Objective

To evaluate how the risk of unexpected newborn complications among term births varied by time of birth for 12.4 million full-term singleton births in the United States.

Study design

A population-based nationwide study. Exposures included time of birth, divided into four shifts and 42 distributed 4-h intervals. Logistic regression estimated the variations in the risk of unexpected newborn complications.

Result

The risk of unexpected newborn complications was higher during night shifts (OR 1.13, 95% CI: 1.12–1.14) and on weekends than on day shifts and weekdays. The risk of seizures and a 5-min Apgar score ≤3 increased steadily at the start of day shifts (07:00), while the risks of transfer, assisted ventilation ≥6 h, and neonatal death remained stable during day shifts. All outcomes increased during night shifts, peaking between 23:00 and 06:59.

Conclusion

Unexpected newborn complications were more frequent during night shifts and weekends, particularly between 23:00 and 06:59.