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Objective <p>Improve regional clinical care for infants with neonatal encephalopathy presumed to be due to hypoxic-ischemic encephalopathy (HIE) by developing a clinical data registry.</p> Study design <p>We developed a regional multicenter registry of newborns at risk for HIE and leveraged data collected within the registry to design and monitor biannually quality improvement metrics in a collaborative effort among site investigators.</p> Result <p>Over the 3 years since beginning our improvement efforts, we have demonstrated positive trends in all three initial metrics decided on by our investigators: increasing the cord blood gas acquisition in high-risk deliveries (median 74–87%); increasing neurological exam and encephalopathy score documentation in infants with perinatal acidosis (17–36%); and decreasing the incidence of infants discharged on anti-seizure medication (60–29%).</p> Conclusion <p>In addition to providing hypothesis-generating research data, local and regional registry data can be successfully utilized for quality improvement efforts across multiple hospitals.</p>

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Harnessing a neonatal encephalopathy registry for regional quality improvement efforts

  • 期刊论文

  • 发表日期：

    2026年1月5日

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  • Fatima M. Al-Sammak,
  • Joshua C. Euteneuer,
  • Nick Townley,
  • Amanda O. Johnson,
  • Ann Anderson Berry,
  • Eric S. Peeples

摘要

Objective

Improve regional clinical care for infants with neonatal encephalopathy presumed to be due to hypoxic-ischemic encephalopathy (HIE) by developing a clinical data registry.

Study design

We developed a regional multicenter registry of newborns at risk for HIE and leveraged data collected within the registry to design and monitor biannually quality improvement metrics in a collaborative effort among site investigators.

Result

Over the 3 years since beginning our improvement efforts, we have demonstrated positive trends in all three initial metrics decided on by our investigators: increasing the cord blood gas acquisition in high-risk deliveries (median 74–87%); increasing neurological exam and encephalopathy score documentation in infants with perinatal acidosis (17–36%); and decreasing the incidence of infants discharged on anti-seizure medication (60–29%).

Conclusion

In addition to providing hypothesis-generating research data, local and regional registry data can be successfully utilized for quality improvement efforts across multiple hospitals.