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Objective <p>To examine the association of admission NICU capacity strain with neonatal mortality and morbidity.</p> Study design <p>2008–2021 South Carolina cohort using linked vital statistics and discharge data of 22–44 weeks GA infants, born at hospitals with ≥ level 2 unit and ≥5 births &lt;34 weeks GA/year. The exposure was deciles of admission capacity strain, defined as the sum of infants ≤44 weeks GA with a congenital anomaly plus infants &lt;34 weeks GA. The primary outcome was a composite of mortality and term and preterm complications. We used Poisson generalized linear mixed models to examine the association of exposure with outcome adjusting for patient and hospital characteristics.</p> Results <p>We studied 64,647 infants from 30 hospitals. High capacity strain was associated with increased risk of mortality and morbidity adjusting for patient/hospital factors (for example, tenth decile aIRR 1.14, 95% CI 1.03–1.27).</p> Conclusion <p>Capacity strain is associated with adverse NICU outcomes.</p>

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The association of NICU capacity strain with neonatal mortality and morbidity

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年10月20日

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  • Elizabeth G. Salazar,
  • Molly Passarella,
  • Brielle Formanowski,
  • Jeannette Rogowski,
  • Erika M. Edwards,
  • Scott D. Halpern,
  • Ciaran Phibbs,
  • Scott A. Lorch

摘要

Objective

To examine the association of admission NICU capacity strain with neonatal mortality and morbidity.

Study design

2008–2021 South Carolina cohort using linked vital statistics and discharge data of 22–44 weeks GA infants, born at hospitals with ≥ level 2 unit and ≥5 births <34 weeks GA/year. The exposure was deciles of admission capacity strain, defined as the sum of infants ≤44 weeks GA with a congenital anomaly plus infants <34 weeks GA. The primary outcome was a composite of mortality and term and preterm complications. We used Poisson generalized linear mixed models to examine the association of exposure with outcome adjusting for patient and hospital characteristics.

Results

We studied 64,647 infants from 30 hospitals. High capacity strain was associated with increased risk of mortality and morbidity adjusting for patient/hospital factors (for example, tenth decile aIRR 1.14, 95% CI 1.03–1.27).

Conclusion

Capacity strain is associated with adverse NICU outcomes.