Scholarlink

Objective <p>To assess pneumothorax prevalence in neonates across gestational age (GA) categories, identify associated variables, and examine the impact of bubble CPAP (b-CPAP) implementation.</p> Study design <p>A cohort of 58,706 infants born at three hospitals over six years was analyzed, grouped by GA: ≥35 weeks, 29–34 weeks, and ≤28 weeks. Pneumothorax cases were matched with controls, and prevalence before and after b-CPAP adoption was compared.</p> Results <p>Pneumothorax occurred in 310 infants (0.53%): 0.39% in ≥35 weeks, 4.0% in 29–34 weeks, and 4.6% in ≤28 weeks GA. Most cases occurred within 24 hours of birth, especially in ≥35 weeks (76%). In the ≥35-week group, pneumothorax was associated with male sex, chorioamnionitis, and delivery room CPAP. In the 29–34-week group, it was linked to small for gestational age, maternal diabetes, and surfactant use. In ≤28-week infants, delivery room intubation was the primary risk factor. Pneumothorax prevalence in non-intubated infants was unchanged after b-CPAP implementation (0.35% vs. 0.41%; aOR = 0.85, 95% CI: 0.62–1.16; <i>P</i> = 0.35).</p> Conclusion <p>Delivery room interventions, not NICU b-CPAP use, were associated with neonatal pneumothorax.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Pneumothorax in newborns: a cohort study from three NICUs

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年9月4日

查看全文
  • Mohsen A. A. Farghaly,
  • Mahmoud A. M. Ali,
  • Ceyda Acun,
  • Vanishree Nandakumar,
  • Hatem Eltaly,
  • Mohamed A. Mohamed,
  • Hany Aly

摘要

Objective

To assess pneumothorax prevalence in neonates across gestational age (GA) categories, identify associated variables, and examine the impact of bubble CPAP (b-CPAP) implementation.

Study design

A cohort of 58,706 infants born at three hospitals over six years was analyzed, grouped by GA: ≥35 weeks, 29–34 weeks, and ≤28 weeks. Pneumothorax cases were matched with controls, and prevalence before and after b-CPAP adoption was compared.

Results

Pneumothorax occurred in 310 infants (0.53%): 0.39% in ≥35 weeks, 4.0% in 29–34 weeks, and 4.6% in ≤28 weeks GA. Most cases occurred within 24 hours of birth, especially in ≥35 weeks (76%). In the ≥35-week group, pneumothorax was associated with male sex, chorioamnionitis, and delivery room CPAP. In the 29–34-week group, it was linked to small for gestational age, maternal diabetes, and surfactant use. In ≤28-week infants, delivery room intubation was the primary risk factor. Pneumothorax prevalence in non-intubated infants was unchanged after b-CPAP implementation (0.35% vs. 0.41%; aOR = 0.85, 95% CI: 0.62–1.16; P = 0.35).

Conclusion

Delivery room interventions, not NICU b-CPAP use, were associated with neonatal pneumothorax.