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Objective <p>Determine the impact of standardization of care and counseling on survival and morbidities of neonates born at 22–23 weeks gestation.</p> Design <p>Retrospective cohort study of 244 neonates born at 22–23 weeks gestation between 2015 and 2023 in a large healthcare system. The primary outcome was survival of neonates receiving intensive care to NICU discharge. Secondary outcomes included morbidities and resource utilization.</p> Results <p>Neonates born at 22–23 weeks received more intensive care after care standardization (OR 5.4 (95% CI 2.3–12.6), <i>p</i> &lt; 0.0001). Survival remained stable (aOR 0.93 (95% CI 0.32–2.7), <i>p</i> = 0.89) despite more neonates born at 22 weeks receiving intensive care. Resource utilization remained stable.</p> Conclusions <p>Standardizing counseling and care increased the provision of antenatal steroids and intensive care for neonates born at 22 weeks gestation. This allowed neonates born at 22 weeks to survive to discharge without increasing morbidity and resource utilization.</p>

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The impact of standardization of care for neonates born at 22–23 weeks gestation

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年2月4日

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  • Faris N. Al Gharaibeh,
  • DonnaMaria E. Cortezzo,
  • Amy T. Nathan,
  • James M. Greenberg

摘要

Objective

Determine the impact of standardization of care and counseling on survival and morbidities of neonates born at 22–23 weeks gestation.

Design

Retrospective cohort study of 244 neonates born at 22–23 weeks gestation between 2015 and 2023 in a large healthcare system. The primary outcome was survival of neonates receiving intensive care to NICU discharge. Secondary outcomes included morbidities and resource utilization.

Results

Neonates born at 22–23 weeks received more intensive care after care standardization (OR 5.4 (95% CI 2.3–12.6), p < 0.0001). Survival remained stable (aOR 0.93 (95% CI 0.32–2.7), p = 0.89) despite more neonates born at 22 weeks receiving intensive care. Resource utilization remained stable.

Conclusions

Standardizing counseling and care increased the provision of antenatal steroids and intensive care for neonates born at 22 weeks gestation. This allowed neonates born at 22 weeks to survive to discharge without increasing morbidity and resource utilization.