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<p>This pioneering study investigated the real-life effectiveness of single-pill combination (SPC) antihypertensive therapy in patients with uncontrolled blood pressure (BP) and cardiovascular risk factors. After treatment with olmesartan medoxomil/amlodipine besylate/hydrochlorothiazide for 24 weeks, adults with apparent resistant hypertension had significantly reduced systolic BP and approximately 80% achieved target BP. SPC therapy may improve adherence in patients with pseudo-resistant hypertension and is a potentially effective treatment for resistant hypertension.</p>

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Effectiveness of single-pill combination olmesartan/amlodipine/hydrochlorothiazide therapy in patients with apparent resistant hypertension

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月14日

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  • Jaewon Oh,
  • Wonho Kim,
  • Gee-Hee Kim,
  • Hack-Lyoung Kim,
  • Sang-Don Park,
  • Kyung Wan Min,
  • Dongkeun Hyun,
  • Jun Hwa Hong,
  • Soo Lim,
  • Ji-Hwan Bae,
  • Jinho Shin

摘要

This pioneering study investigated the real-life effectiveness of single-pill combination (SPC) antihypertensive therapy in patients with uncontrolled blood pressure (BP) and cardiovascular risk factors. After treatment with olmesartan medoxomil/amlodipine besylate/hydrochlorothiazide for 24 weeks, adults with apparent resistant hypertension had significantly reduced systolic BP and approximately 80% achieved target BP. SPC therapy may improve adherence in patients with pseudo-resistant hypertension and is a potentially effective treatment for resistant hypertension.