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<p>The multidimensional echocardiographic features associated with BP level are unclear. This study aimed to identify the multidimensional echocardiographic features associated with BP. In total, 2&#xa0;092 adult participants (aged ≥18 years) with hypertension who underwent echocardiography in Beijing between July 2017 and January 2020 as part of the Multi-provincial Cohort for Hypertension study were enrolled. The associations between BP levels and echocardiographic features were investigated by multivariate regression analysis. After multivariable adjustment, a 1 SD (15.4 mmHg) increase in systolic BP was associated with a 0.21-mm increment (95% CI 0.06–0.35) in left atrial diameter, a 2.17-g/m<sup>2</sup> increment (95% CI 1.46–2.88) in LV mass index, a 0.25-mm increment (95% CI 0.11–0.39) in ascending aorta diameter and a 0.03 decrement (95% CI −0.04, −0.01) in the E/A ratio. A 1 SD (10.1 mmHg) increase in diastolic BP was associated with a 1.51-g/m<sup>2</sup> increment (95% CI 0.80–2.21) in LV mass index, a 0.46-mm increment (95% CI 0.31–0.61) in aortic root diameter, a 0.77-mm increment (95% CI 0.63–0.91) in ascending aorta diameter, and a 0.05 decrement (95% CI −0.07, −0.04) in E/A ratio. In conclusion, specific echocardiographic features were associated with the BP level. LV structure, ascending aorta diameter, and the E/A ratio were associated with systolic and diastolic BP. Left atrial diameter was positively associated only with systolic BP, and aortic root diameter was positively associated only with diastolic BP. These echocardiographic features may be valuable for early identification of target organ damage caused by elevated BP.</p>

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Profiles of echocardiographic features associated with blood pressure in patients with hypertension

  • 期刊论文

  • 发表日期：

    2025年6月5日

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  • Wenlang Zhao,
  • Mingdan Wang,
  • Pan Zhou,
  • Ziyu Wang,
  • Xuan Deng,
  • Jiangtao Li,
  • Na Yang,
  • Lizhen Han,
  • Zhao Yang,
  • Yue Qi,
  • Jing Liu

摘要

The multidimensional echocardiographic features associated with BP level are unclear. This study aimed to identify the multidimensional echocardiographic features associated with BP. In total, 2 092 adult participants (aged ≥18 years) with hypertension who underwent echocardiography in Beijing between July 2017 and January 2020 as part of the Multi-provincial Cohort for Hypertension study were enrolled. The associations between BP levels and echocardiographic features were investigated by multivariate regression analysis. After multivariable adjustment, a 1 SD (15.4 mmHg) increase in systolic BP was associated with a 0.21-mm increment (95% CI 0.06–0.35) in left atrial diameter, a 2.17-g/m2 increment (95% CI 1.46–2.88) in LV mass index, a 0.25-mm increment (95% CI 0.11–0.39) in ascending aorta diameter and a 0.03 decrement (95% CI −0.04, −0.01) in the E/A ratio. A 1 SD (10.1 mmHg) increase in diastolic BP was associated with a 1.51-g/m2 increment (95% CI 0.80–2.21) in LV mass index, a 0.46-mm increment (95% CI 0.31–0.61) in aortic root diameter, a 0.77-mm increment (95% CI 0.63–0.91) in ascending aorta diameter, and a 0.05 decrement (95% CI −0.07, −0.04) in E/A ratio. In conclusion, specific echocardiographic features were associated with the BP level. LV structure, ascending aorta diameter, and the E/A ratio were associated with systolic and diastolic BP. Left atrial diameter was positively associated only with systolic BP, and aortic root diameter was positively associated only with diastolic BP. These echocardiographic features may be valuable for early identification of target organ damage caused by elevated BP.