Scholarlink

<p>In this study, an efficient and convenient three component cyclization protocol is presented for the development of synthetically important chromeno[4,3-<i>b</i>]chromene/chromeno[2,3‐<i>d</i>]pyrimidine derivatives via lemon juice mediated reaction of substituted salicylaldehyde, 4-hydroxycoumarin/1,3-dimethylbarbituric acid and electron rich arenes. As lemon juice is cheap, readily accessible, biodegradable, and nontoxic, the present method is environmentally benign and economical. Moreover, our development is simple to handle, produces high yields, tolerates many functional groups, provides easy isolation, and allows for scalable synthesis—all of which align with the basic principles of green chemistry.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Lemon juice mediated environmentally benign synthesis of functionalized chromeno[4,3-b]chromene/chromeno[2,3‐d]pyrimidine derivatives via one-pot three component reaction

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年3月2日

查看全文
  • Yogesh Bhaskar Singh Tanwer,
  • Suman Sourabh,
  • Sabyasachi Bhunia,
  • Sanchari Pal,
  • Debjit Das

摘要

In this study, an efficient and convenient three component cyclization protocol is presented for the development of synthetically important chromeno[4,3-b]chromene/chromeno[2,3‐d]pyrimidine derivatives via lemon juice mediated reaction of substituted salicylaldehyde, 4-hydroxycoumarin/1,3-dimethylbarbituric acid and electron rich arenes. As lemon juice is cheap, readily accessible, biodegradable, and nontoxic, the present method is environmentally benign and economical. Moreover, our development is simple to handle, produces high yields, tolerates many functional groups, provides easy isolation, and allows for scalable synthesis—all of which align with the basic principles of green chemistry.