Scholarlink

<p>Endodontic treatment failure can result from persistent bacteria, inadequate cleaning and sealing of root canals, and missed canals. The resilience of bacteria such as <i>F. nucleatum</i> and <i>E. faecalis</i> within the root canal system is a significant cause of failed endodontic treatment. Calcium hydroxide (CaOH), a widely utilized intracanal medicament, has demonstrated antimicrobial properties. However, its ability to consistently achieve culture-negative root canals after chemo-mechanical procedures remains inconsistent. This study aimed to evaluate and compare the antimicrobial efficacy of CaOH and BlueM gel against <i>F. nucleatum</i> and <i>E. faecalis</i> biofilms using dentin discs. Sterilized dentin discs were prepared from extracted human teeth. <i>F. nucleatum</i> and <i>E. faecalis</i> were grown on these discs and then treated with either CaOH or BlueM gel. Antimicrobial efficacy was assessed by quantifying colony-forming unit counts. BlueM gel demonstrated significantly greater antimicrobial efficacy than CaOH against both <i>F. nucleatum</i> and <i>E. faecalis</i> biofilms. Both agents exhibited substantial antimicrobial activity against the biofilms. BlueM gel showed superior antimicrobial effectiveness against endodontic pathogens such as <i>F. nucleatum</i> and <i>E. faecalis</i> compared to CaOH.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Antimicrobial efficacy of blueM gel and calcium hydroxide against F. nucleatum and E. faecalis biofilm: an ex-vivo study

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年7月28日

查看全文
  • Yahya Raja Alharbi,
  • Swati Srivastava,
  • Hanin Alsalhi,
  • Khawlah Almohimeed,
  • Mohammad Alduraibi,
  • Ahmed Nabil

摘要

Endodontic treatment failure can result from persistent bacteria, inadequate cleaning and sealing of root canals, and missed canals. The resilience of bacteria such as F. nucleatum and E. faecalis within the root canal system is a significant cause of failed endodontic treatment. Calcium hydroxide (CaOH), a widely utilized intracanal medicament, has demonstrated antimicrobial properties. However, its ability to consistently achieve culture-negative root canals after chemo-mechanical procedures remains inconsistent. This study aimed to evaluate and compare the antimicrobial efficacy of CaOH and BlueM gel against F. nucleatum and E. faecalis biofilms using dentin discs. Sterilized dentin discs were prepared from extracted human teeth. F. nucleatum and E. faecalis were grown on these discs and then treated with either CaOH or BlueM gel. Antimicrobial efficacy was assessed by quantifying colony-forming unit counts. BlueM gel demonstrated significantly greater antimicrobial efficacy than CaOH against both F. nucleatum and E. faecalis biofilms. Both agents exhibited substantial antimicrobial activity against the biofilms. BlueM gel showed superior antimicrobial effectiveness against endodontic pathogens such as F. nucleatum and E. faecalis compared to CaOH.