Scholarlink

<p>The primary objective of this investigation was to optimize the energy output by arc discharge machine parameters to synthesize Magnetic-based carbon nanomaterial and use it as an anti-bacterial. The energy gap of the electrode material and the output energy created play a vital role in the nano size, shape, and structure produced. However, the parameters suitable for nano creation are still under research. Iron-based carbon (Fe@C) nanocomposite was fully characterized by transmission electron microscope (HR-TEM), X-ray Diffraction (XRD), UV/Visible Spectrophotometer (UV), Fourier transform infrared spectroscopy (FTIR), Particle size analyzer (PZ), and Zeta potential. Nanoparticles created in a spherical shape with a diameter of 18&#xa0;nm wrapped in carbon. The energy gap of the sample measured gives us two values: 2.9&#xa0;eV for C and 2.2&#xa0;eV for Fe. Short-term antibiotics and overcoming bacterial resistance are great challenges during infection. To resolve this problem, Fe@C nanocomposite was prepared to overcome these problems. In vitro experiments of Fe@C nanocomposite revealed that the antibacterial activity is concentration-dependent. Additionally, it was determined that <i>S. aureus</i> 2 was the most sensitive strain, which led to its selection for additional investigations. The interaction between Fe@C nanoparticles and bacterial cells is characterized by an increase in reactive oxygen species (ROS). At the concentrations that were tested, the prepared nanoparticles exhibited mild anti-diabetic properties. The synthesized nanoparticles were evaluated for their antioxidant properties by scavenging DPPH. The IC50 of Fe@C was 210.7 ± 4.09&#xa0;µg/mL, as indicated by the data. The nanoparticles that were synthesized were evaluated for their anti-inflammatory properties. The data indicated that the IC50 of Fe@C was 51.75 ± 1.69&#xa0;µg/mL. The cell cytotoxic concentration (CC50) is 401.38 ± 8.12&#xa0;µg/mL.</p> Graphical Abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Plasma creator device to produce Fe@C core–shell: anti-bacterial, anti-oxidant, anti-diabetic, anti-inflammatory, and cytotoxic activities

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年8月13日

查看全文
  • Salhah H. Alrefaee

摘要

The primary objective of this investigation was to optimize the energy output by arc discharge machine parameters to synthesize Magnetic-based carbon nanomaterial and use it as an anti-bacterial. The energy gap of the electrode material and the output energy created play a vital role in the nano size, shape, and structure produced. However, the parameters suitable for nano creation are still under research. Iron-based carbon (Fe@C) nanocomposite was fully characterized by transmission electron microscope (HR-TEM), X-ray Diffraction (XRD), UV/Visible Spectrophotometer (UV), Fourier transform infrared spectroscopy (FTIR), Particle size analyzer (PZ), and Zeta potential. Nanoparticles created in a spherical shape with a diameter of 18 nm wrapped in carbon. The energy gap of the sample measured gives us two values: 2.9 eV for C and 2.2 eV for Fe. Short-term antibiotics and overcoming bacterial resistance are great challenges during infection. To resolve this problem, Fe@C nanocomposite was prepared to overcome these problems. In vitro experiments of Fe@C nanocomposite revealed that the antibacterial activity is concentration-dependent. Additionally, it was determined that S. aureus 2 was the most sensitive strain, which led to its selection for additional investigations. The interaction between Fe@C nanoparticles and bacterial cells is characterized by an increase in reactive oxygen species (ROS). At the concentrations that were tested, the prepared nanoparticles exhibited mild anti-diabetic properties. The synthesized nanoparticles were evaluated for their antioxidant properties by scavenging DPPH. The IC50 of Fe@C was 210.7 ± 4.09 µg/mL, as indicated by the data. The nanoparticles that were synthesized were evaluated for their anti-inflammatory properties. The data indicated that the IC50 of Fe@C was 51.75 ± 1.69 µg/mL. The cell cytotoxic concentration (CC50) is 401.38 ± 8.12 µg/mL.

Graphical Abstract