Scholarlink

<p>The medicinal herb <i>Centella asiatica</i> is a potential source of bioactive compounds and offers a wide range of biological activities that can be effectively utilised by selecting suitable extraction methods. Traditional extraction methods that reduce the efficiency and activity of the herb can be replaced by choosing efficient green technologies that require less extraction time. Therefore, this study was subjected to evaluate microwave treatment at different conditions, such as power (180&#xa0;W, 360&#xa0;W, 540&#xa0;W), time 15s, 30s, and 90s and solid-liquid ratio (15, 22.5, and 30 mL/g). The highest yield of secondary metabolites was obtained at 540&#xa0;W, 90&#xa0;s, and a solid-liquid ratio of 22.5 mL/g. The biological activities were tested and resulted in antioxidant activity (78.78 ± 0.05%), total phenol content (225 ± 0.75 mgGAE/mL), total flavonoid content (54.80 ± 0.24&#xa0;mg QE/mL), total flavanol (25 ± 0.87 mgQE/mL), and enzyme inhibitory activity respectively (α- amylase 55.50 ± 0.62%, α- glucosidase 66.97 ± 0.72%) and antimicrobial activity against Gram-negative bacteria <i>Escherichia coli</i> 3&#xa0;mm inhibition zone and Gram-positive bacteria <i>Bacillus subtilis</i> 4&#xa0;mm as inhibition zone. The best-treated extract was infused into a strawberry-yoghurt food system at various concentrations (10&#xa0;mg, 25&#xa0;mg, and 40&#xa0;mg). It was found to contain high levels of antioxidants (84.33 ± 0.54%) and phenolic compounds (170.53 ± 0.89&#xa0;mg GAE/g), and it exhibited strong enzyme inhibition against α-amylase (83.52 ± 0.76%) and α-glucosidase (84.52 ± 0.06%). Based on the promising outcomes, it is recommended to further investigate the pharmacokinetic behaviour and safety aspects of microwave-treated <i>C. asiatica</i> extracts before large-scale application in functional foods. In conclusion, microwave-assisted extraction proves to be an efficient green technology to maximise bioactive recovery and enhance the therapeutic potential of <i>C. asiatica</i>-infused food systems.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Effect of microwave pretreatment on the extraction of bioactives from Centella asiatica and its utilization in developing smoothies

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年4月4日

查看全文
  • Athira R. S. Pillai,
  • Yuvraj Bhosale Khasherao,
  • Bharath Kokkuvayil Ramadas,
  • Ansu Sara Eapen,
  • Swarup Roy

摘要

The medicinal herb Centella asiatica is a potential source of bioactive compounds and offers a wide range of biological activities that can be effectively utilised by selecting suitable extraction methods. Traditional extraction methods that reduce the efficiency and activity of the herb can be replaced by choosing efficient green technologies that require less extraction time. Therefore, this study was subjected to evaluate microwave treatment at different conditions, such as power (180 W, 360 W, 540 W), time 15s, 30s, and 90s and solid-liquid ratio (15, 22.5, and 30 mL/g). The highest yield of secondary metabolites was obtained at 540 W, 90 s, and a solid-liquid ratio of 22.5 mL/g. The biological activities were tested and resulted in antioxidant activity (78.78 ± 0.05%), total phenol content (225 ± 0.75 mgGAE/mL), total flavonoid content (54.80 ± 0.24 mg QE/mL), total flavanol (25 ± 0.87 mgQE/mL), and enzyme inhibitory activity respectively (α- amylase 55.50 ± 0.62%, α- glucosidase 66.97 ± 0.72%) and antimicrobial activity against Gram-negative bacteria Escherichia coli 3 mm inhibition zone and Gram-positive bacteria Bacillus subtilis 4 mm as inhibition zone. The best-treated extract was infused into a strawberry-yoghurt food system at various concentrations (10 mg, 25 mg, and 40 mg). It was found to contain high levels of antioxidants (84.33 ± 0.54%) and phenolic compounds (170.53 ± 0.89 mg GAE/g), and it exhibited strong enzyme inhibition against α-amylase (83.52 ± 0.76%) and α-glucosidase (84.52 ± 0.06%). Based on the promising outcomes, it is recommended to further investigate the pharmacokinetic behaviour and safety aspects of microwave-treated C. asiatica extracts before large-scale application in functional foods. In conclusion, microwave-assisted extraction proves to be an efficient green technology to maximise bioactive recovery and enhance the therapeutic potential of C. asiatica-infused food systems.