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<p>Athyrium filix-femina, commonly known as Lady Fern, demonstrates notable antibacterial capacity based on scientific studies. Its role in this context stems from the presence of various bioactive compounds within the plant that can inhibit the growth of bacteria. This study evaluated the phytochemical composition, antioxidant properties, and antimicrobial activities of ethanolic extract of <i>Athyrium filix-femina</i> (AE). Total phenolic content (TPC) and total flavonoid content (TFC) were determined colorimetrically, yielding values of 25.066&#xa0;mg gallic acid equivalents (GAE)/g and 5.97&#xa0;mg quercetin equivalents (QE)/g, respectively. Antioxidant capacities were assessed via DPPH, ABTS, FRAP, and phosphomolybdenum assays, with AE demonstrating notable radical-scavenging and reducing power, particularly in the FRAP assay (IC₅₀ = 15.646&#xa0;µg/mL). Antimicrobial activity was tested against six bacterial strains using the disc diffusion method, revealing significant efficacy against <i>Escherichia coli</i> (inhibition zone = 9.67&#xa0;mm at 0.6&#xa0;mg/mL). These findings underscore <i>A. filix-femina</i> as a potent source of bioactive compounds with antioxidant and antimicrobial potential, suggesting its applicability in agriculture, food, pharmaceutical, and cosmetic industries.</p>

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Phytochemical profile, antioxidant capacity, and antimicrobial activity of Athyrium filix-femina ethanolic extract

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月31日

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  • Thanh-Tam-Ngoc Huynh,
  • Diem-Huynh-Ngoc Vo,
  • Thi-Tho Nguyen,
  • Van-Ba Nguyen,
  • Thuy-Trang Pham,
  • Thao-My-Thi Tran,
  • Phu-Tho Nguyen,
  • Huu-Thanh Nguyen

摘要

Athyrium filix-femina, commonly known as Lady Fern, demonstrates notable antibacterial capacity based on scientific studies. Its role in this context stems from the presence of various bioactive compounds within the plant that can inhibit the growth of bacteria. This study evaluated the phytochemical composition, antioxidant properties, and antimicrobial activities of ethanolic extract of Athyrium filix-femina (AE). Total phenolic content (TPC) and total flavonoid content (TFC) were determined colorimetrically, yielding values of 25.066 mg gallic acid equivalents (GAE)/g and 5.97 mg quercetin equivalents (QE)/g, respectively. Antioxidant capacities were assessed via DPPH, ABTS, FRAP, and phosphomolybdenum assays, with AE demonstrating notable radical-scavenging and reducing power, particularly in the FRAP assay (IC₅₀ = 15.646 µg/mL). Antimicrobial activity was tested against six bacterial strains using the disc diffusion method, revealing significant efficacy against Escherichia coli (inhibition zone = 9.67 mm at 0.6 mg/mL). These findings underscore A. filix-femina as a potent source of bioactive compounds with antioxidant and antimicrobial potential, suggesting its applicability in agriculture, food, pharmaceutical, and cosmetic industries.