Medicinal plants of genus Curculigo: exploring traditional applications, phytochemistry, ethnopharmacological perspective
摘要
The genus Curculigo is a perennial herb with wide range of therapeutic activities. This genus Curculigo belongs to the family Hypoxidaceae, found widely distributed in the Indo-Asian countries. Since the ancient time usage of Curculigo is practiced traditionally for tonics and treatment of various diseases, not the least it is used as a natural dye and its leaves are used for binding of foods and stuffs. To sum up the divergent of Genus Curculigo in pharmacological aspect, data of literature review published since 1996 till 2024 were collected from PubMed, Scopus, and research gate. Many important phytochemicals were isolated from this genus. Out of the 28 types of Curculigo species, Curculigo orchioides, Curculigo capitulata, Curculigo pilosa, Curculigo latifolia, Curculigo breviscapa, Curculigo sinensis, Curculigo crassifolia, Curculigo glabrescens are most widely known and out of which curculigo orchioides is the most exploited medicinal herb and is already listed in the endangered species because of its wide range of therapeutic potential as compared to other Curculigo species. Curculigo orchioides content phenolic compounds, chlorophenol compounds, monosaccharides and polysaccharides, cyclic peptides, and terpenoids. Wide range of pharmacological activities such as antiosteoporosis, anti-carcinogen, anti-microbial, immunostimulatory, aphrodisiacs, anti-diabetic, anti-hepatitis anti-hypertensive, anti-inflammatory, anti-asthmatic, hepatoprotective, neuroprotective, nephroprotective, anti-ulcer, anti-oxidant, anti-dementia, anti-depressant are seen in the extract of Curculigo orchioides. More than 61 known compounds have been isolated which is as much as more than 91 compounds. Most of the phenolic compounds and norlignan compounds were isolated from the rhizomes extract. Other Curculigo species also possess the same activity as covered by Curculigo orchioides. This review will serve as an insight in guiding the researchers for further investigation, isolation and development of more useful components from this genus.
Graphical Abstract