Scholarlink

<p>2-mercaptopyrimidine-mediated synthesis of 3,3’ (sulfonylbis(methylene))bis(chlorobenzene) has been carried out for quantitative intermolecular noncovalent interactions analysis and antioxidant activity. The analysis of non-covalent interactions was performed through X-ray crystallography, Hirshfeld surface analysis, and NCI calculations. Additionally, molecular docking and in vitro studies were conducted to assess antioxidant activity. Docking studies, ADMET, and drug-likeness results indicated that this compound exhibits promising antioxidant activity.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Synthesis and crystal structure analysis of sulfone based derivative for non-covalent interaction analysis and antioxidant activity

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年6月22日

查看全文
  • Amit Jaiswal,
  • Manima Mishra,
  • Awdhesh Kumar Pal,
  • Ranjeet Kumar

摘要

2-mercaptopyrimidine-mediated synthesis of 3,3’ (sulfonylbis(methylene))bis(chlorobenzene) has been carried out for quantitative intermolecular noncovalent interactions analysis and antioxidant activity. The analysis of non-covalent interactions was performed through X-ray crystallography, Hirshfeld surface analysis, and NCI calculations. Additionally, molecular docking and in vitro studies were conducted to assess antioxidant activity. Docking studies, ADMET, and drug-likeness results indicated that this compound exhibits promising antioxidant activity.