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<p>Furo[2,3-<i>b</i>]pyridines have garnered great interest owning to their broad applicability in pharmaceutical design and materials science. Consequently, the development of efficient and practical routes to access furo[2,3-<i>b</i>]pyridine derivatives is a topic of significance in both medicinal chemistry and materials research. Among the diverse synthetic strategies, domino annulation reactions have emerged as particularly powerful methodologies, enabling the one-step assembly of diverse cyclic architectures. In recent years, notable progress has been achieved in the synthesis of furo[2,3-<i>b</i>]pyridine derivatives through domino annulations. This review summarizes the advances in this field since 2014, offering a concise overview of key developments.</p>

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Recent advances in the synthesis of furo[2,3-b]pyridine derivatives through novel domino annulations

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年1月28日

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  • Hui Mao,
  • Cuiying Li,
  • Haiyun Yang,
  • Liejin Zhou,
  • Xin Lv

摘要

Furo[2,3-b]pyridines have garnered great interest owning to their broad applicability in pharmaceutical design and materials science. Consequently, the development of efficient and practical routes to access furo[2,3-b]pyridine derivatives is a topic of significance in both medicinal chemistry and materials research. Among the diverse synthetic strategies, domino annulation reactions have emerged as particularly powerful methodologies, enabling the one-step assembly of diverse cyclic architectures. In recent years, notable progress has been achieved in the synthesis of furo[2,3-b]pyridine derivatives through domino annulations. This review summarizes the advances in this field since 2014, offering a concise overview of key developments.