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Background <p>Adolescent idiopathic scoliosis (AIS) is commonly treated conservatively, with Computer-aided design and manufacturing (CAD/CAM) technology has emerged as a modern and innovative approach in brace therapy, The superiority of CAD/CAM braces over traditional hand-made orthotics remains unestablished, prompting an investigation into their comparative efficacy.</p> Objective <p>To systematically review and meta-analyze the available evidence on the effectiveness of CAD/CAM braces for AIS, incorporating biomechanical analysis, finite element analysis, or 3D printing.</p> Methods <p>A systematic search was conducted in PubMed, Web of Science (WOS), Embase, MEDLINE, Cochrane Library, China National Knowledge Infrastructure (CNKI), WanFang, VIP, and China Biology Medicine disc (CBM) databases through April 1, 2024. The search targeted randomized controlled trials (RCTs) and randomized controlled crossover trials (RCT-CTs). Eligible studies were assessed for quality, and data were extracted for meta-analysis.</p> Results <p>The initial search identified 13 trials involving 539 participants (1629 individual data points). After applying inclusion criteria, 11 trials with 469 participants (1424 individual data points) were included in the meta-analysis. The results indicated that CAD/CAM braces provided only marginally better or equivalent outcomes compared to traditional braces. The therapeutic advantages of CAD/CAM methods were not conclusively demonstrated by the current evidence.</p> Conclusion <p>The evidence base for the superiority of CAD/CAM braces in AIS treatment is insufficient. Future research with larger sample sizes and higher methodological quality is essential to enhance the evidence-based approach to medical practice in this field.</p>

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Efficacy of computer-aided design and computer-aided manufacturing-based braces for adolescent idiopathic scoliosis: a systematic review and meta-analysis

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年8月1日

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  • Xiaogang Shen,
  • Dailiang Zhang,
  • Fei Yuan,
  • Qian Peng,
  • Chunjiang Lv,
  • Hongzhe Qi,
  • Mengyan Zhao,
  • Gongzhen Chen,
  • Hao Ye,
  • Gan Gao,
  • Tao Guo

摘要

Background

Adolescent idiopathic scoliosis (AIS) is commonly treated conservatively, with Computer-aided design and manufacturing (CAD/CAM) technology has emerged as a modern and innovative approach in brace therapy, The superiority of CAD/CAM braces over traditional hand-made orthotics remains unestablished, prompting an investigation into their comparative efficacy.

Objective

To systematically review and meta-analyze the available evidence on the effectiveness of CAD/CAM braces for AIS, incorporating biomechanical analysis, finite element analysis, or 3D printing.

Methods

A systematic search was conducted in PubMed, Web of Science (WOS), Embase, MEDLINE, Cochrane Library, China National Knowledge Infrastructure (CNKI), WanFang, VIP, and China Biology Medicine disc (CBM) databases through April 1, 2024. The search targeted randomized controlled trials (RCTs) and randomized controlled crossover trials (RCT-CTs). Eligible studies were assessed for quality, and data were extracted for meta-analysis.

Results

The initial search identified 13 trials involving 539 participants (1629 individual data points). After applying inclusion criteria, 11 trials with 469 participants (1424 individual data points) were included in the meta-analysis. The results indicated that CAD/CAM braces provided only marginally better or equivalent outcomes compared to traditional braces. The therapeutic advantages of CAD/CAM methods were not conclusively demonstrated by the current evidence.

Conclusion

The evidence base for the superiority of CAD/CAM braces in AIS treatment is insufficient. Future research with larger sample sizes and higher methodological quality is essential to enhance the evidence-based approach to medical practice in this field.