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<p>Juvenile psoriasis arthritis (JPsA) is defined as arthritis of unknown cause in children &lt; 16&#xa0;years when psoriasis or psoriasis-like characteristics, e.g., dactylitis or nail changes, are present in addition to arthritis. The etiology is unknown; the prevalence is about&#xa0;10–15&#xa0;per 100,000 and the annual incidence rate is between 2&#xa0;and 3&#xa0;per 100,000. Within the first 6&#xa0;months the disease, oligoarthritis generally develops; symmetric polyarthritis is observed only rarely at disease onset. Isolated swelling of a single small joint, particularly a single toe, is characteristic for the disease. Nonsteroidal anti-inflammatory drugs are established as first-line therapy. Depending on the clinical picture, disease-modifying drugs, such as methotrexate, sulfasalazine or biologics can also be used. The prognosis for JPsA is generally poor. In a large percentage of patients, signs of active arthritis still persist after 5&#xa0;years of treatment. The clinical symptoms, diagnosis, and treatment of JPsA are described using a case study.</p>

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Ein 16-jähriges Mädchen mit einer Schwellung von 3 Fingern seit mehreren Monaten

  • 期刊论文

  • 发表日期：

    2026年1月20日

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  • Christian Huemer

摘要

Juvenile psoriasis arthritis (JPsA) is defined as arthritis of unknown cause in children < 16 years when psoriasis or psoriasis-like characteristics, e.g., dactylitis or nail changes, are present in addition to arthritis. The etiology is unknown; the prevalence is about 10–15 per 100,000 and the annual incidence rate is between 2 and 3 per 100,000. Within the first 6 months the disease, oligoarthritis generally develops; symmetric polyarthritis is observed only rarely at disease onset. Isolated swelling of a single small joint, particularly a single toe, is characteristic for the disease. Nonsteroidal anti-inflammatory drugs are established as first-line therapy. Depending on the clinical picture, disease-modifying drugs, such as methotrexate, sulfasalazine or biologics can also be used. The prognosis for JPsA is generally poor. In a large percentage of patients, signs of active arthritis still persist after 5 years of treatment. The clinical symptoms, diagnosis, and treatment of JPsA are described using a case study.