Background <p>The concept of entrustable professional activities (EPAs) is increasingly being integrated into undergraduate education and postgraduate training. However, there are various ways to create EPAs.</p> Objective <p>The aim of this work is to identify the most common reasons for consulting a&#xa0;general practitioner in order to create a&#xa0;source for the development of future EPAs.</p> Materials and methods <p>A&#xa0;secondary data analysis of routine data from eight general medical practices (<i>n</i> = 145,298 patients) in Baden-Württemberg was conducted. The observation period covered the first quarter of 2000 (2000Q1) to the second quarter of 2025 (2025Q2). The reasons for consultation were categorised according to the International Classification of Primary Care, second edition (ICPC-2) chapters, supplemented by categories for children, prevention and multimorbidity. Frequencies were calculated at patient, annual, quarterly and daily levels. The analysis also included care tasks such as issuing certificates of incapacity to work and referrals.</p> Results <p>Approximately 2.1&#xa0;million practice visits were analysed. Patients with multimorbidity (17% of the cohort) constituted the most common category of consultation reasons (50% of practice contacts on a&#xa0;daily basis), followed by musculoskeletal concerns and circulatory and social problems.</p> Conclusion <p>The results provide evidence to build common future EPAs specifically for general medical care needs.</p>