<p>Maintaining healthy life in old age (healthy aging) is an important social challenge. An effective approach to realizing healthy aging involves providing personalized healthcare through disease prevention, early diagnostics, and optimal treatments. Nanobiodevices and quantum life sciences have tremendous potential to revolutionize current techniques for disease prevention, diagnostics, and treatment via the efficient analyses of biomolecules, bioparticles, pathogens, and cells. In this review, we outline our research on nanobiodevices and quantum life sciences for future healthcare, including cancer diagnostics, pathogen detection, in vivo imaging-guided therapy, and intracellular sensing for stem cell quality checks.</p> Graphical abstract <p></p>