Background <p>Healthcare professionals in Afghanistan face extraordinary challenges due to systemic and cultural factors, with sleep quality emerging as a critical determinant of their physical and mental well-being. Poor sleep quality has been strongly linked to higher suicidal thoughts and diminished job performance, compounding the difficulties faced in the understaffed and high-pressure environment of government hospitals in Kabul City.</p> Objective <p>The purpose of this research is to explore the interrelations between sleep quality, suicidal ideation, and job effectiveness in healthcare professionals, with a view to developing focused interventions.</p> Methods <p>A Correlational study was carried out among 130 health workers in Kabul City government hospitals. Data were gathered through standardized tools: Pittsburgh Sleep Quality Index (PSQI), Beck Scale for Suicidal Ideation (BSSI), and Job Efficacy Scale. Statistical analyses included Spearman correlation and descriptive statistics.</p> Results <p>An astounding 60% of the healthcare workers had poor sleep quality, and suicidal thoughts and sleep quality were strongly positively correlated (r = 0.328, p &lt; 0.001). There was no correlation between job efficacy, suicidal ideation, and sleep quality.</p> Conclusion <p>These results underscore the imperative need for sleep hygiene interventions for healthcare workers in Kabul City. Improved quality of sleep can alleviate suicidal ideation and general well-being, leading to better healthcare outcomes. Larger sample sizes and culturally specific interventions must take high priority in future studies to explore these associations.</p>