Background <p>Laparoscopic cholecystectomy (LC) is a standard procedure in general surgery, but residents may lack the confidence to perform it as primary surgeons. This study aims to assess the confidence levels of senior general surgery residents in Saudi Arabia regarding LC.</p> Objective <p>To examine the factors influencing confidence among senior general surgery residents in performing laparoscopic cholecystectomy as primary surgeons.</p> Methods <p>A cross-sectional survey was distributed to senior general surgery residents (PGY4 and PGY5) across Saudi Arabia. The survey assessed procedural exposure, confidence levels, and institutional resources. Data were analyzed for associations between confidence levels, gender, and surgical volume.</p> Results <p>Of the 78 respondents, 62.8% had performed fewer than 50 LCs as primary surgeons. Confidence levels varied significantly by gender, with male residents expressing higher confidence. A significant association was found between higher case volume and greater confidence (<i>p</i> &lt; 0.05). Residents with access to simulation-based training reported higher confidence levels.</p> Conclusion <p>Senior general surgery residents in Saudi Arabia show moderate confidence in performing laparoscopic cholecystectomy, with gender disparities and limited exposure affecting their skills. Increased exposure and simulation-based training are recommended to enhance resident preparedness.</p>