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<p>The left ventricular pressure–volume relationship is a&#xa0;core concept in cardiac physiology, characterized by the heart’s nonlinear behavior, where increased preload leads to greater contractile force. The end-systolic pressure–volume relationship defines the ventricle’s maximal contractility. Its slope, the end-systolic elastance, serves as a&#xa0;load-independent marker of contractility.</p>

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Die linksventrikuläre Herzarbeit und die ventrikuloarterielle Kopplung

  • 期刊论文

  • 发表日期：

    2026年1月20日

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  • Walter Hasibeder,
  • Johann Knotzer

摘要

The left ventricular pressure–volume relationship is a core concept in cardiac physiology, characterized by the heart’s nonlinear behavior, where increased preload leads to greater contractile force. The end-systolic pressure–volume relationship defines the ventricle’s maximal contractility. Its slope, the end-systolic elastance, serves as a load-independent marker of contractility.