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<p>Climbing too quickly to altitudes above 2500–3000 m carries the risk of developing one of the three forms of acute high-altitude illness: acute mountain sickness (AMS), a&#xa0;syndrome of nonspecific symptoms including headache, fatigue, dizziness, and nausea; high-altitude cerebral edema (HACE), which is characterized by ataxia and decreased consciousness up to coma; and high-altitude pulmonary edema (HAPE), a&#xa0;noncardiogenic form of pulmonary edema resulting from excessive hypoxic pulmonary vasoconstriction. All three of these diseases can develop at any time from several hours to 5&#xa0;days following ascent to high altitude. Although AMS is usually self-limiting, HACE and HAPE represent life-threatening emergencies that require prompt intervention.</p>

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Akute Höhenerkrankungen

  • 期刊论文

  • 发表日期：

    2025年8月6日

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  • Felix Breßmer,
  • Marc Moritz Berger,
  • Peter Paal

摘要

Climbing too quickly to altitudes above 2500–3000 m carries the risk of developing one of the three forms of acute high-altitude illness: acute mountain sickness (AMS), a syndrome of nonspecific symptoms including headache, fatigue, dizziness, and nausea; high-altitude cerebral edema (HACE), which is characterized by ataxia and decreased consciousness up to coma; and high-altitude pulmonary edema (HAPE), a noncardiogenic form of pulmonary edema resulting from excessive hypoxic pulmonary vasoconstriction. All three of these diseases can develop at any time from several hours to 5 days following ascent to high altitude. Although AMS is usually self-limiting, HACE and HAPE represent life-threatening emergencies that require prompt intervention.