Listening for Biosignals: Bio-Mechanoacoustic Emissions and Recording Systems for Wearable Monitoring of Vital Sounds
摘要
Auscultation - the practice of listening to sounds emanating from the heart, lungs, and other organs - has been a mainstay of noninvasive physiological monitoring and diagnosis since at least the 17th century BCE. Coincident with the contemporary push towards population health, telemedicine, and longitudinal outpatient monitoring, advances in both wearable electronics and data analytics have enabled new wearable sensors and systems targeting mechanoacoustic biosignals. These signals are an attractive option for health monitoring as they are passively transduced, low frequency, and can directly identify mechanical abnormalities which lack an associated bioelectrical signal change (e.g., a heart murmur that does not appear on an electrocardiogram). This work explores the viability of wearable mechanoacoustic sensors and their potential future role in precision medicine, examining their historical context, fundamental theory of operation, and the relevance of specific techniques to various pathologies. Finally, the advantages and limitations of various transduction schemes are reviewed, along with relevant areas of active research and potential future research directions.