Scholarlink

<p>Nanoparticles are small particles with diameters ranging from 1 to 100&#xa0;nm. Recent trends and advancements in nanotechnology have revolutionized various fields, particularly medicine, technology, and the environmental sciences. Various types of nanoparticles are being employed to assist in biomedical applications due to their small size and ideal properties in the diagnosis and treatment of biological problems, e.g., cancer. This review explains the types of nanoparticles used for biomedical applications, e.g., drug delivery, hyperthermia, photoablation therapy, bioimaging, and nanoparticle-integrated biosensing and wearable diagnostic platforms. This review paper introduces a new integrative review model in which classes of nanoparticles are linked with application specific mechanism, safety profiles, and translational design requirements as opposed to discussing them separately. This review, unlike most of the available studies, includes a cross-platform comparative study of metallic, polymeric, inorganic, and upcoming hybrid nanomaterials used in therapy. Process-structure-performance relationships are addressed in the manuscript, which includes the transport engineering thinking and parametric optimization planning, affecting the membrane-based and controlled release systems. This review paper adds new information to the existing literature by incorporating the recent developments made in quantum dots, graphene-based nanomaterials, and nanocomposite hydrogels and nano-enabled microfluidic electrochemical systems for non-invasive health monitoring. The manuscript also summarises the evidence from several different disciplines to suggest a single roadmap towards designing and clinical translation of next-generation nanoparticles. Emerging technologies, recent developments, and challenges of nanoparticles are reviewed in detail. The limitations of nanoparticles in the current literature and recommended future research opportunities are also highlighted. The suggestions and recommendations include interdisciplinary collaboration, the use of established methods for drug characterisation, and narrowing the gap between preclinical research and clinical application.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Nanoparticles in Biomedical Applications: Recent Trends, Challenges, and Future Directions

  • 期刊论文

  • 发表日期：

    2026年3月23日

查看全文
  • Noura Zouaghi,
  • Imran Shah,
  • Muhammad Kamran Khan,
  • Muneeza Rauf,
  • Asif khan,
  • Muhammad Ali Khan,
  • Ahmed Aamouche

摘要

Nanoparticles are small particles with diameters ranging from 1 to 100 nm. Recent trends and advancements in nanotechnology have revolutionized various fields, particularly medicine, technology, and the environmental sciences. Various types of nanoparticles are being employed to assist in biomedical applications due to their small size and ideal properties in the diagnosis and treatment of biological problems, e.g., cancer. This review explains the types of nanoparticles used for biomedical applications, e.g., drug delivery, hyperthermia, photoablation therapy, bioimaging, and nanoparticle-integrated biosensing and wearable diagnostic platforms. This review paper introduces a new integrative review model in which classes of nanoparticles are linked with application specific mechanism, safety profiles, and translational design requirements as opposed to discussing them separately. This review, unlike most of the available studies, includes a cross-platform comparative study of metallic, polymeric, inorganic, and upcoming hybrid nanomaterials used in therapy. Process-structure-performance relationships are addressed in the manuscript, which includes the transport engineering thinking and parametric optimization planning, affecting the membrane-based and controlled release systems. This review paper adds new information to the existing literature by incorporating the recent developments made in quantum dots, graphene-based nanomaterials, and nanocomposite hydrogels and nano-enabled microfluidic electrochemical systems for non-invasive health monitoring. The manuscript also summarises the evidence from several different disciplines to suggest a single roadmap towards designing and clinical translation of next-generation nanoparticles. Emerging technologies, recent developments, and challenges of nanoparticles are reviewed in detail. The limitations of nanoparticles in the current literature and recommended future research opportunities are also highlighted. The suggestions and recommendations include interdisciplinary collaboration, the use of established methods for drug characterisation, and narrowing the gap between preclinical research and clinical application.