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<p>Additive manufacturing or three-dimensional (3D) printing, is transforming the pharmaceutical sciences by allowing complex drug delivery systems, dosage forms, and biomedical devices to be developed customized for patients. This technology is allowing the precise control of shape, internal structure, and drug release mechanisms. Thereby characterizing a patient-specific therapy and impact on health outcomes. Over the last few years, 3D printing has been developed for their use in pharmaceutical applications including wound dressings, surgical, and tissue engineering, as well as in personalized medicine. The flexible nature of the technology allows for both the rapid prototyping and low-cost manufacturing of complex designs on demand that would not be possible with traditional manufacturing techniques. However, despite the advantages there are many hurdles to overcome before the technology can be realized in wider implementation in pharmaceutical applications, like regulations, material biocompatibility, scale up, and standardization. The current paper reviews the history and state of the art technologies, commonly utilized materials, applications in pharmaceuticals, case studies, and barriers still facing the 3D printing.</p>

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Engineering Medicines: A Comprehensive Review on 3D Printing in Pharmaceuticals

  • 期刊论文

  • 发表日期：

    2026年3月5日

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  • Shreejit Das,
  • Abhishek Kumar,
  • Radheshyam Jena,
  • Nilesh Kumar Singh,
  • Vancha Harish

摘要

Additive manufacturing or three-dimensional (3D) printing, is transforming the pharmaceutical sciences by allowing complex drug delivery systems, dosage forms, and biomedical devices to be developed customized for patients. This technology is allowing the precise control of shape, internal structure, and drug release mechanisms. Thereby characterizing a patient-specific therapy and impact on health outcomes. Over the last few years, 3D printing has been developed for their use in pharmaceutical applications including wound dressings, surgical, and tissue engineering, as well as in personalized medicine. The flexible nature of the technology allows for both the rapid prototyping and low-cost manufacturing of complex designs on demand that would not be possible with traditional manufacturing techniques. However, despite the advantages there are many hurdles to overcome before the technology can be realized in wider implementation in pharmaceutical applications, like regulations, material biocompatibility, scale up, and standardization. The current paper reviews the history and state of the art technologies, commonly utilized materials, applications in pharmaceuticals, case studies, and barriers still facing the 3D printing.