Scholarlink

<p>This study highlights the eco-friendly synthesis and potent antimicrobial potential of silver nanoparticles (Ag NPs) using <i>Ziziphus mauritiana</i> leaf extract as a natural reducing and capping agent. The unique properties of Ag NPs make them significantly less toxic and endow them with a broad spectrum of antibacterial activities, leading to numerous potential applications. In the present study, Ag NPs were synthesized via a bio-reduction method using silver nitrate as a metallic precursor and varying concentrations of <i>Ziziphus mauritiana</i> extract. The extract exhibited strong potential for the rapid reduction of silver ions, facilitating the formation of stable nanoparticles. The synthesized Ag NPs were characterized by visible spectroscopy and scanning electron microscopy (SEM). Absorption surface plasmon resonance (SPR) peaks appeared in the range of 415–439&#xa0;nm, confirming the formation of nanoparticles. In comparison, the SEM analysis revealed spherical particles with a size distribution ranging from 10 to 25&#xa0;nm. The in vitro antibacterial activity of the colloidal Ag NPs and plant extract was evaluated against <i>Escherichia Coli</i> using different concentrations (C1 = 100&#xa0;µg/ml, C2 = 50&#xa0;µg/ml, C3 = 25&#xa0;µg/ml) using the well diffusion method. The antifungal activity was also examined against <i>Candida Albicans</i>, showing low minimum inhibitory concentration (MIC) values and significant fungal growth inhibition. The mode of action involves the disruption of fungal cell membrane integrity and oxidative stress induction. The green-synthesized Ag NPs demonstrated excellent antibacterial and antifungal properties, suggesting their potential as alternative antimicrobial agents.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Eco-Friendly Biosynthesis of Stable Silver Nanoparticles from Ziziphus mauritiana Leaves: Structural Characterization and Antimicrobial Evaluation

  • 期刊论文

  • 发表日期：

    2026年2月17日

查看全文
  • Shoaeb Mohammad Syed,
  • Shivam Kulkarni,
  • Mayur Patil,
  • Kranti Satpute,
  • Mahesh Sonkamble

摘要

This study highlights the eco-friendly synthesis and potent antimicrobial potential of silver nanoparticles (Ag NPs) using Ziziphus mauritiana leaf extract as a natural reducing and capping agent. The unique properties of Ag NPs make them significantly less toxic and endow them with a broad spectrum of antibacterial activities, leading to numerous potential applications. In the present study, Ag NPs were synthesized via a bio-reduction method using silver nitrate as a metallic precursor and varying concentrations of Ziziphus mauritiana extract. The extract exhibited strong potential for the rapid reduction of silver ions, facilitating the formation of stable nanoparticles. The synthesized Ag NPs were characterized by visible spectroscopy and scanning electron microscopy (SEM). Absorption surface plasmon resonance (SPR) peaks appeared in the range of 415–439 nm, confirming the formation of nanoparticles. In comparison, the SEM analysis revealed spherical particles with a size distribution ranging from 10 to 25 nm. The in vitro antibacterial activity of the colloidal Ag NPs and plant extract was evaluated against Escherichia Coli using different concentrations (C1 = 100 µg/ml, C2 = 50 µg/ml, C3 = 25 µg/ml) using the well diffusion method. The antifungal activity was also examined against Candida Albicans, showing low minimum inhibitory concentration (MIC) values and significant fungal growth inhibition. The mode of action involves the disruption of fungal cell membrane integrity and oxidative stress induction. The green-synthesized Ag NPs demonstrated excellent antibacterial and antifungal properties, suggesting their potential as alternative antimicrobial agents.