Scholarlink

<p><i>Annona muricata</i> has long been utilized in traditional medicine and biomedicine. In this study, we developed an eco-friendly method for synthesizing zinc oxide nanoparticles (CS-ZnO NPs) using <i>A. muricata</i> leaf extract. The synthesized CS-ZnO NPs were characterized by UV–visible spectroscopy (UV–vis), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and field emission scanning electron microscopy with energy-dispersive X-ray analysis (FESEM-EDAX). UV–vis analysis confirmed nanoparticle formation with a distinct absorption peak at 255&#xa0;nm. FTIR identified functional groups responsible for nanoparticle stabilization, while XRD verified their crystalline nature. SEM images revealed predominantly spherical particles and EDAX confirmed the elemental composition of zinc and oxygen. The CS-ZnO NPs exhibited strong antibacterial activity against Gram-positive <i>Enterococcus faecalis</i> with a 10&#xa0;mm zone of inhibition, along with notable antioxidant activity as demonstrated by DPPH (76.56%), ABTS (77.24%) and TAC (79.81%) assays. Additionally, the nanoparticles showed promising antidiabetic potential, inhibiting α-amylase (79.18%) and α-glucosidase (73.22%). Overall, these findings suggest that green-synthesized CS-ZnO NPs from <i>A. muricata</i> leaves possess significant antimicrobial, antioxidant and antidiabetic properties, making them highly promising for the biomedical applications.</p> Graphical Abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Phytogenic Synthesis of Chitosan-Doped Zinc Oxide Nano Composites Using Annona muricata Linn: Evaluation of Antibacterial, Antioxidant and Antidiabetic Activities

  • 期刊论文

  • 发表日期：

    2025年10月27日

查看全文
  • Malarkodi Raja,
  • Shanmugam Gurusamy,
  • A Gokulakrishnan,
  • Latha Sellapillai,
  • Sudha Durairajan,
  • Suganya Murugan,
  • Manickam Gomathi,
  • A. Amjad Hussain,
  • Dharmalingam Kirubakaran,
  • Mukesh Kumar Dharmalingam Jothinathan

摘要

Annona muricata has long been utilized in traditional medicine and biomedicine. In this study, we developed an eco-friendly method for synthesizing zinc oxide nanoparticles (CS-ZnO NPs) using A. muricata leaf extract. The synthesized CS-ZnO NPs were characterized by UV–visible spectroscopy (UV–vis), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and field emission scanning electron microscopy with energy-dispersive X-ray analysis (FESEM-EDAX). UV–vis analysis confirmed nanoparticle formation with a distinct absorption peak at 255 nm. FTIR identified functional groups responsible for nanoparticle stabilization, while XRD verified their crystalline nature. SEM images revealed predominantly spherical particles and EDAX confirmed the elemental composition of zinc and oxygen. The CS-ZnO NPs exhibited strong antibacterial activity against Gram-positive Enterococcus faecalis with a 10 mm zone of inhibition, along with notable antioxidant activity as demonstrated by DPPH (76.56%), ABTS (77.24%) and TAC (79.81%) assays. Additionally, the nanoparticles showed promising antidiabetic potential, inhibiting α-amylase (79.18%) and α-glucosidase (73.22%). Overall, these findings suggest that green-synthesized CS-ZnO NPs from A. muricata leaves possess significant antimicrobial, antioxidant and antidiabetic properties, making them highly promising for the biomedical applications.

Graphical Abstract