<p>Titanium has long been recognized as a cornerstone material in the biomedical field, particularly in dental and orthopedic implants, owing to its remarkable mechanical strength, biocompatibility, and natural passivation behavior. Historically, its use marked a turning point in implantology by significantly reducing tissue rejection and enhancing osseointegration. Despite these advantages, titanium is not entirely immune to corrosion, especially in complex physiological environments that include fluctuating pH, oxidative agents, proteins, and microbial activity. These factors can compromise implant longevity and lead to biological complications. Recent research has focused on titanium corrosion in body and oral environments, emphasizing how biofilms, reactive oxygen species, and organic molecules accelerate degradation. Consequently, innovative surface modifications, such as bioactive coatings, nanostructured oxides, and graphene barriers, are being developed to enhance corrosion resistance and antibacterial effects. The future of titanium implant technology lies in the development of multifunctional, biomimetic coatings that enhance long-term stability and support tissue regeneration. Concurrently, the integration of artificial intelligence (AI) for optimizing implant design, predicting corrosion behavior, and tailoring surface modifications offers a promising avenue. These advancements necessitate a multidisciplinary approach, combining materials science, biomedical engineering, and data-driven technologies to achieve enhanced implant performance in complex physiological environments.</p>

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Historical and Emerging Trends in Titanium Implant Technologies: Surface Innovation and AI Integration

  • Hala Hrir,
  • Abderrazzak Boudouma,
  • Abdelghani Ghanam,
  • Omar Ait Layachi,
  • Othmane Zakir,
  • Elmati Khoumri

摘要

Titanium has long been recognized as a cornerstone material in the biomedical field, particularly in dental and orthopedic implants, owing to its remarkable mechanical strength, biocompatibility, and natural passivation behavior. Historically, its use marked a turning point in implantology by significantly reducing tissue rejection and enhancing osseointegration. Despite these advantages, titanium is not entirely immune to corrosion, especially in complex physiological environments that include fluctuating pH, oxidative agents, proteins, and microbial activity. These factors can compromise implant longevity and lead to biological complications. Recent research has focused on titanium corrosion in body and oral environments, emphasizing how biofilms, reactive oxygen species, and organic molecules accelerate degradation. Consequently, innovative surface modifications, such as bioactive coatings, nanostructured oxides, and graphene barriers, are being developed to enhance corrosion resistance and antibacterial effects. The future of titanium implant technology lies in the development of multifunctional, biomimetic coatings that enhance long-term stability and support tissue regeneration. Concurrently, the integration of artificial intelligence (AI) for optimizing implant design, predicting corrosion behavior, and tailoring surface modifications offers a promising avenue. These advancements necessitate a multidisciplinary approach, combining materials science, biomedical engineering, and data-driven technologies to achieve enhanced implant performance in complex physiological environments.