<p>Poly (lactic acid) (PLA) is a bioderived and biodegradable thermoplastic widely used in various applications; however, its brittleness limits its mechanical performance. To address this issue, this study develops fully biodegradable PLA/Poly (butylene adipate-co-terephthalate) (PBAT) blends compatibilized with epoxidized castor oil (ECO), providing a sustainable alternative to conventional non-biodegradable compatibilizers. PLA/PBAT blends with varying ECO concentrations (0.5, 1.0, and 1.5%) were prepared via melt mixing and characterized using multiple techniques. Fourier transform infrared (FTIR) spectroscopy confirmed effective interactions between ECO, PLA, and PBAT, enhancing compatibility. Thermal properties were analyzed using differential scanning calorimetry (DSC), while contact angle measurements demonstrated an increase in hydrophilicity, confirming their suitability for biomedical applications. Mechanical testing revealed that PLA/PBAT blends with 1.0% ECO exhibited significantly improved elongation at break and impact strength without compromising tensile strength. Field emission scanning electron microscopy (FESEM) showed uniform PBAT dispersion and enhanced interfacial morphology. Furthermore, cell proliferation, adhesion activity, and hemocompatibility assessments confirmed excellent biocompatibility, highlighting their potential for biomedical use. These findings suggest that ECO-modified PLA/PBAT blends offer a promising route for developing high-performance, biodegradable materials suitable for biomedical applications.</p>

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Development of Toughened Poly (lactic acid) by Melt Blending with Poly (butylene adipate-co-terephthalate) Using Epoxidized Castor Oil as a Compatibilizer for Biomedical Applications

  • K. P. Ajeya,
  • Y. P. Naveen,
  • K. T. Vishnu,
  • G. S. Kariyappa Gowda,
  • S. M. Anush,
  • K. Amita,
  • K. Prashantha

摘要

Poly (lactic acid) (PLA) is a bioderived and biodegradable thermoplastic widely used in various applications; however, its brittleness limits its mechanical performance. To address this issue, this study develops fully biodegradable PLA/Poly (butylene adipate-co-terephthalate) (PBAT) blends compatibilized with epoxidized castor oil (ECO), providing a sustainable alternative to conventional non-biodegradable compatibilizers. PLA/PBAT blends with varying ECO concentrations (0.5, 1.0, and 1.5%) were prepared via melt mixing and characterized using multiple techniques. Fourier transform infrared (FTIR) spectroscopy confirmed effective interactions between ECO, PLA, and PBAT, enhancing compatibility. Thermal properties were analyzed using differential scanning calorimetry (DSC), while contact angle measurements demonstrated an increase in hydrophilicity, confirming their suitability for biomedical applications. Mechanical testing revealed that PLA/PBAT blends with 1.0% ECO exhibited significantly improved elongation at break and impact strength without compromising tensile strength. Field emission scanning electron microscopy (FESEM) showed uniform PBAT dispersion and enhanced interfacial morphology. Furthermore, cell proliferation, adhesion activity, and hemocompatibility assessments confirmed excellent biocompatibility, highlighting their potential for biomedical use. These findings suggest that ECO-modified PLA/PBAT blends offer a promising route for developing high-performance, biodegradable materials suitable for biomedical applications.