<p>Man has always been prone to burns due to his daily contact with various causes, whether at home, at work, in a plane crash, in a car accident, in war, in bushfires, or elsewhere. For several years, dromedary hump oil, derived from the hump of <i>Camelus dromedarius</i>, has been known in North Africa for its beneficial properties, especially in dermatological contexts. It has been used to treat burns, dermal infections, chronic wounds, and atopic dermatitis. Honey is considered one of the most effective natural ointments for burns and wounds. This study aims to evaluate the anti-inflammatory, wound-healing, and antinociceptive properties of the crude hump oil of <i>Camelus dromedarius</i>, as well as its physicochemical characterization. Also, we aimed to compare hump oil capacity to treat wounds to thyme honey. Our physical characterization results showed: fat content, 99.78&#xa0;g⁄100&#xa0;g; free fatty acids (as oleic acid), 0.48&#xa0;g⁄100&#xa0;g; peroxide value, 0.85 Meq.&#xa0;O2/kg; iodine value 46,9&#xa0;g⁄100&#xa0;g; density, 0,840 and viscosity, 93.20cP at 20&#xa0;°C. Besides, the anti-inflammatory effect of dromedary hump oil against carrageenan-induced paw edema showed 92% inhibition at the 6th hour, compared to Diclofenac, which showed 90% inhibition at the same hour. Moreover, the antinociceptive test of dromedary hump oil against acetic acid showed 95% protection, higher than that of Tramadol (91%).</p>

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Dromedary hump oil: From its physicochemical characterization to, anti-inflammatory, wound healing and antinociceptive potentials

  • Beybeti Ishagh,
  • Widad Tbatou,
  • Asmae ElGhouizi,
  • Tarik Elaraj,
  • Zineb Benziane Ouartini,
  • Driss Ousaaid,
  • Badiaa Lyoussi

摘要

Man has always been prone to burns due to his daily contact with various causes, whether at home, at work, in a plane crash, in a car accident, in war, in bushfires, or elsewhere. For several years, dromedary hump oil, derived from the hump of Camelus dromedarius, has been known in North Africa for its beneficial properties, especially in dermatological contexts. It has been used to treat burns, dermal infections, chronic wounds, and atopic dermatitis. Honey is considered one of the most effective natural ointments for burns and wounds. This study aims to evaluate the anti-inflammatory, wound-healing, and antinociceptive properties of the crude hump oil of Camelus dromedarius, as well as its physicochemical characterization. Also, we aimed to compare hump oil capacity to treat wounds to thyme honey. Our physical characterization results showed: fat content, 99.78 g⁄100 g; free fatty acids (as oleic acid), 0.48 g⁄100 g; peroxide value, 0.85 Meq. O2/kg; iodine value 46,9 g⁄100 g; density, 0,840 and viscosity, 93.20cP at 20 °C. Besides, the anti-inflammatory effect of dromedary hump oil against carrageenan-induced paw edema showed 92% inhibition at the 6th hour, compared to Diclofenac, which showed 90% inhibition at the same hour. Moreover, the antinociceptive test of dromedary hump oil against acetic acid showed 95% protection, higher than that of Tramadol (91%).