<p>Concrete is composed of many components such as cement, aggregates, and water. Concrete being a strong building material, it is widely utilized in the building sector for making various products with the addition of bound ingredients to enhance its strength and durability properties. Continued industrial development is critical to a country’s economic growth and progress. There is a huge demand for animal hides and skin which are processed to make leather products. The leather industry is one of the main sectors that generate good revenue for the Indian government. The amount of waste generated by this industry is significant and is classified as hazardous due to its complex content of toxic chemicals, heavy metals, and other contaminating substances. The Central Pollution Control Board (CPCB), established by the government, lists the leather industry as one of India’s major polluting industries. As the substantial quantities of solid waste generated by the tannery industry have a harmful effect on the environment and its inhabitants, it is essential to employ an effective waste management solution. The main aim is tannery sludge as a partial replacement for fine aggregate in the construction of a concrete block. The rising cost of watercourse sand, the use of sludge as a construction material. The concrete grades used for this investigation are M₂₀, M₂₅, and M₃₀, and the fine aggregate is partially replaced with industrial sludge in varied percentages of 0% to 30%. The mechanical characteristics, properties and toughness of the prepared concrete block are examined through ANOVA and Life Cycle Assessment.</p>