Challenge <p>Biomimicry, biomimetic, and bioinspired (B³) approaches to medical device and technology design are a broad and multidisciplinary framework for engineering design. A typical final design assignment for a semester-long design course requires students to apply course knowledge and design principles to generate a proof-of-concept medical device prototype by the end of the semester. However, there is an opportunity for students to explore and apply B³ design principles throughout the semester rather than for a single summative final design assignment.</p> Novel Initiative <p>This paper describes how three formative assignments are implemented in an undergraduate medical device design technical elective through the framework of inquiry-based learning. The scaffolded assignments include building B³-inspired prototypes using LEGO® SERIOUS PLAY®, learning B³-inspired design through immersive technology and medical device redesign, and learning B³-inspired design through immersion in nature.</p> Reflection <p>The scaffolded inquiry-based learning assignments provided students the opportunity to develop B³-inspired design skills and competencies before applying them to a final design assignment. Assessments demonstrate that learning outcomes were met, students were engaged and interacted with the scaffolded assignments well, and students learned a new design ecosystem with which to use to develop solutions for medical problems.</p>