<p>Most vegetable vendors are in densely populated towns and cities, where they offer an extensive variety of vegetables to consumers. However, many barriers that are faced by African indigenous vegetable (AIV) vendors hinder their effective operation, hence affecting their essential livelihood option and income. The current study assesses the market barriers of AIV vendors in the City of Tshwane, Gauteng, South Africa. This study employed a proportional sampling technique to gather data from 210 indigenous vegetable vendors in the City of Tshwane, Gauteng Province, South Africa. Descriptive statistics and ordered logistic regression analysis were used to analyze data for this study. The results revealed the significant influence of age, gender, experience, household income, and competitive prices supplied by indigenous vegetable vendors as minor and major market barriers among indigenous vegetable vendors. The study demonstrates the importance of addressing market barriers faced by AIV vendors to improve their livelihoods, food and nutritional security and income. It is recommended that indigenous vegetable vendors should offer competitive prices. Addressing this setback enables them to reduce the probability of facing major and minor marketing barriers. This study is in line with the agenda for sustainable development goals 1 and 2 aimed to reduce extreme poverty and ensure zero hunger by guaranteeing global access to nutritious and safe food.</p>