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Introduction and Importance <p>Calcific myonecrosis is a rare entity characterized by coagulative and liquefactive necrosis with calcifications of the entire muscle mass of the involved compartment secondary to post-traumatic compartment syndrome. There is limited literature on the rare disease with technical difficulties and pitfalls of operative procedures in these patients.</p> Presentation of Case <p>A 52-year-old male presented with complaints of swelling over his right leg with discharging sinus over the past 2&#xa0;years following a surgical intervention. He was diagnosed as a case of calcific myonecrosis based on history and clinico-radio-histological correlation and was managed successfully with en&#xa0;bloc excision with vacuum-assisted closure (VAC) of wound.</p> Clinical Discussion <p>A rare musculoskeletal condition is characterized by muscle necrosis and extensive calcification within a limb compartment, typically following post-traumatic compartment syndrome involving muscle and neurovascular structures. Diagnosis relies heavily on radiological findings, such as calcifications and adjacent bone erosions, while histopathology is crucial to exclude malignancy. A high index of clinical suspicion is essential for timely identification.</p> Conclusion <p>Calcific myonecrosis requires a multi-factorial approach to reach to a diagnosis, with ruling out the differentials and proper preoperative plan are the key to success. If un-infected, it is a “Touch me not disease”; however, through debridement or en-mass excision of compartment with VAC therapy should be considered for infected cases.</p>

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Calcific Myonecrosis: Case Report of a Rare Clinical Presentation and Literature Review

  • 期刊论文

  • 发表日期：

    2025年6月4日

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  • Vikas Maheshwari,
  • Danish V,
  • Vikas Olkha,
  • Mohit Dhingra,
  • Cury Sharma,
  • Anil Regmi

摘要

Introduction and Importance

Calcific myonecrosis is a rare entity characterized by coagulative and liquefactive necrosis with calcifications of the entire muscle mass of the involved compartment secondary to post-traumatic compartment syndrome. There is limited literature on the rare disease with technical difficulties and pitfalls of operative procedures in these patients.

Presentation of Case

A 52-year-old male presented with complaints of swelling over his right leg with discharging sinus over the past 2 years following a surgical intervention. He was diagnosed as a case of calcific myonecrosis based on history and clinico-radio-histological correlation and was managed successfully with en bloc excision with vacuum-assisted closure (VAC) of wound.

Clinical Discussion

A rare musculoskeletal condition is characterized by muscle necrosis and extensive calcification within a limb compartment, typically following post-traumatic compartment syndrome involving muscle and neurovascular structures. Diagnosis relies heavily on radiological findings, such as calcifications and adjacent bone erosions, while histopathology is crucial to exclude malignancy. A high index of clinical suspicion is essential for timely identification.

Conclusion

Calcific myonecrosis requires a multi-factorial approach to reach to a diagnosis, with ruling out the differentials and proper preoperative plan are the key to success. If un-infected, it is a “Touch me not disease”; however, through debridement or en-mass excision of compartment with VAC therapy should be considered for infected cases.